Database of mammalian genes
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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for IL1B (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000187
activation of MAPK activity
IDA
GO:0001666
response to hypoxia
IEA
GO:0001934
positive regulation of protein phosphorylation
IDA
GO:0001934
positive regulation of protein phosphorylation
NAS
GO:0002439
chronic inflammatory response to antigenic stimulus
IEA
GO:0002711
positive regulation of T cell mediated immunity
IC
GO:0006915
apoptosis
TAS
GO:0006916
anti-apoptosis
IDA
GO:0006954
inflammatory response
IDA
GO:0006954
inflammatory response
IEA
GO:0006954
inflammatory response
NAS
GO:0006955
immune response
IEA
GO:0007165
signal transduction
TAS
GO:0007204
elevation of cytosolic calcium ion concentration
IEA
GO:0007267
cell-cell signaling
TAS
GO:0007566
embryo implantation
TAS
GO:0007568
aging
IEA
GO:0007584
response to nutrient
IEA
GO:0007613
memory
IEA
GO:0008285
negative regulation of cell proliferation
IDA
GO:0009408
response to heat
IEA
GO:0010193
response to ozone
IEA
GO:0010243
response to organic nitrogen
IEA
GO:0010332
response to gamma radiation
IEA
GO:0010575
positive regulation vascular endothelial growth factor production
IDA
GO:0010575
positive regulation vascular endothelial growth factor production
IEA
GO:0010575
positive regulation vascular endothelial growth factor production
ISS
GO:0010829
negative regulation of glucose transport
IEA
GO:0010829
negative regulation of glucose transport
ISS
GO:0014050
negative regulation of glutamate secretion
IEA
GO:0014070
response to organic cyclic compound
IEA
GO:0014805
smooth muscle adaptation
NAS
GO:0019221
cytokine-mediated signaling pathway
IDA
GO:0019221
cytokine-mediated signaling pathway
IEA
GO:0030593
neutrophil chemotaxis
IEA
GO:0030728
ovulation
IEA
GO:0030730
sequestering of triglyceride
IDA
GO:0030949
positive regulation of vascular endothelial growth factor receptor signaling pathway
IC
GO:0031622
positive regulation of fever generation
IEA
GO:0031622
positive regulation of fever generation
ISS
GO:0032308
positive regulation of prostaglandin secretion
IEA
GO:0032308
positive regulation of prostaglandin secretion
ISS
GO:0032355
response to estradiol stimulus
IEA
GO:0032496
response to lipopolysaccharide
IEA
GO:0032725
positive regulation of granulocyte macrophage colony-stimulating factor production
IDA
GO:0032729
positive regulation of interferon-gamma production
IDA
GO:0032755
positive regulation of interleukin-6 production
IEA
GO:0032755
positive regulation of interleukin-6 production
TAS
GO:0032757
positive regulation of interleukin-8 production
IDA
GO:0032874
positive regulation of stress-activated MAPK cascade
IEA
GO:0033129
positive regulation of histone phosphorylation
NAS
GO:0033198
response to ATP
IEA
GO:0033280
response to vitamin D
IEA
GO:0033591
response to L-ascorbic acid
IEA
GO:0034116
positive regulation of heterotypic cell-cell adhesion
NAS
GO:0035066
positive regulation of histone acetylation
NAS
GO:0035176
social behavior
IEA
GO:0035505
positive regulation of myosin light chain kinase activity
IDA
GO:0035690
cellular response to drug
IDA
GO:0042060
wound healing
IEA
GO:0042102
positive regulation of T cell proliferation
IDA
GO:0042346
positive regulation of NF-kappaB import into nucleus
IDA
GO:0042493
response to drug
IEA
GO:0043065
positive regulation of apoptosis
IEA
GO:0043122
regulation of I-kappaB kinase/NF-kappaB cascade
IDA
GO:0043123
positive regulation of I-kappaB kinase/NF-kappaB cascade
IEA
GO:0043278
response to morphine
IEA
GO:0043407
negative regulation of MAP kinase activity
IEA
GO:0043407
negative regulation of MAP kinase activity
ISS
GO:0043507
positive regulation of JUN kinase activity
IEA
GO:0045080
positive regulation of chemokine biosynthetic process
IEA
GO:0045086
positive regulation of interleukin-2 biosynthetic process
IMP
GO:0045410
positive regulation of interleukin-6 biosynthetic process
IEA
GO:0045429
positive regulation of nitric oxide biosynthetic process
IDA
GO:0045766
positive regulation of angiogenesis
IEA
GO:0045766
positive regulation of angiogenesis
ISS
GO:0045833
negative regulation of lipid metabolic process
IEA
GO:0045833
negative regulation of lipid metabolic process
ISS
GO:0045840
positive regulation of mitosis
IMP
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IEA
GO:0046330
positive regulation of JNK cascade
IEA
GO:0046627
negative regulation of insulin receptor signaling pathway
IEA
GO:0046627
negative regulation of insulin receptor signaling pathway
ISS
GO:0046827
positive regulation of protein export from nucleus
NAS
GO:0050796
regulation of insulin secretion
IDA
GO:0050900
leukocyte migration
IEA
GO:0050995
negative regulation of lipid catabolic process
IDA
GO:0050996
positive regulation of lipid catabolic process
IEA
GO:0050996
positive regulation of lipid catabolic process
ISS
GO:0051044
positive regulation of membrane protein ectodomain proteolysis
IDA
GO:0051091
positive regulation of sequence-specific DNA binding transcription factor activity
IDA
GO:0051092
positive regulation of NF-kappaB transcription factor activity
IDA
GO:0051384
response to glucocorticoid stimulus
IEA
GO:0051781
positive regulation of cell division
IEA
GO:0060355
positive regulation of cell adhesion molecule production
NAS
GO:0060559
positive regulation of calcidiol 1-monooxygenase activity
IDA
GO:0070164
negative regulation of adiponectin secretion
IEA
GO:0070164
negative regulation of adiponectin secretion
ISS
GO:0070374
positive regulation of ERK1 and ERK2 cascade
IEA
GO:0071260
cellular response to mechanical stimulus
IEP
GO:0071310
cellular response to organic substance
IDA
GO:0071639
positive regulation of monocyte chemotactic protein-1 production
IDA
cellular_component
GO:0005576
extracellular region
IEA
GO:0005576
extracellular region
NAS
GO:0005576
extracellular region
TAS
GO:0005615
extracellular space
IEA
GO:0005615
extracellular space
IMP
GO:0005829
cytosol
TAS
GO:0030141
stored secretory granule
IEA
GO:0031982
vesicle
IEA
molecular_function
GO:0005125
cytokine activity
IDA
GO:0005125
cytokine activity
IEA
GO:0005125
cytokine activity
IMP
GO:0005149
interleukin-1 receptor binding
IEA
GO:0005149
interleukin-1 receptor binding
NAS
GO:0008083
growth factor activity
IEA
GO:0019904
protein domain specific binding
IPI
Protein-protein interaction details for IL1B (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
MAPK8IP2
Phenotypic Suppression
genetic
10756100
ZNF675
Phenotypic Suppression
genetic
11751921
UBE2N
Phenotypic Suppression
genetic
11057907
IL1R1
Reconstituted Complex
physical
7878046