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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IL1B (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000187activation of MAPK activityIDA
GO:0001666response to hypoxiaIEA
GO:0001934positive regulation of protein phosphorylationIDA
GO:0001934positive regulation of protein phosphorylationNAS
GO:0002439chronic inflammatory response to antigenic stimulusIEA
GO:0002711positive regulation of T cell mediated immunityIC
GO:0006915apoptosisTAS
GO:0006916anti-apoptosisIDA
GO:0006954inflammatory responseIDA
GO:0006954inflammatory responseIEA
GO:0006954inflammatory responseNAS
GO:0006955immune responseIEA
GO:0007165signal transductionTAS
GO:0007204elevation of cytosolic calcium ion concentrationIEA
GO:0007267cell-cell signalingTAS
GO:0007566embryo implantationTAS
GO:0007568agingIEA
GO:0007584response to nutrientIEA
GO:0007613memoryIEA
GO:0008285negative regulation of cell proliferationIDA
GO:0009408response to heatIEA
GO:0010193response to ozoneIEA
GO:0010243response to organic nitrogenIEA
GO:0010332response to gamma radiationIEA
GO:0010575positive regulation vascular endothelial growth factor productionIDA
GO:0010575positive regulation vascular endothelial growth factor productionIEA
GO:0010575positive regulation vascular endothelial growth factor productionISS
GO:0010829negative regulation of glucose transportIEA
GO:0010829negative regulation of glucose transportISS
GO:0014050negative regulation of glutamate secretionIEA
GO:0014070response to organic cyclic compoundIEA
GO:0014805smooth muscle adaptationNAS
GO:0019221cytokine-mediated signaling pathwayIDA
GO:0019221cytokine-mediated signaling pathwayIEA
GO:0030593neutrophil chemotaxisIEA
GO:0030728ovulationIEA
GO:0030730sequestering of triglycerideIDA
GO:0030949positive regulation of vascular endothelial growth factor receptor signaling pathwayIC
GO:0031622positive regulation of fever generationIEA
GO:0031622positive regulation of fever generationISS
GO:0032308positive regulation of prostaglandin secretionIEA
GO:0032308positive regulation of prostaglandin secretionISS
GO:0032355response to estradiol stimulusIEA
GO:0032496response to lipopolysaccharideIEA
GO:0032725positive regulation of granulocyte macrophage colony-stimulating factor productionIDA
GO:0032729positive regulation of interferon-gamma productionIDA
GO:0032755positive regulation of interleukin-6 productionIEA
GO:0032755positive regulation of interleukin-6 productionTAS
GO:0032757positive regulation of interleukin-8 productionIDA
GO:0032874positive regulation of stress-activated MAPK cascadeIEA
GO:0033129positive regulation of histone phosphorylationNAS
GO:0033198response to ATPIEA
GO:0033280response to vitamin DIEA
GO:0033591response to L-ascorbic acidIEA
GO:0034116positive regulation of heterotypic cell-cell adhesionNAS
GO:0035066positive regulation of histone acetylationNAS
GO:0035176social behaviorIEA
GO:0035505positive regulation of myosin light chain kinase activityIDA
GO:0035690cellular response to drugIDA
GO:0042060wound healingIEA
GO:0042102positive regulation of T cell proliferationIDA
GO:0042346positive regulation of NF-kappaB import into nucleusIDA
GO:0042493response to drugIEA
GO:0043065positive regulation of apoptosisIEA
GO:0043122regulation of I-kappaB kinase/NF-kappaB cascadeIDA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIEA
GO:0043278response to morphineIEA
GO:0043407negative regulation of MAP kinase activityIEA
GO:0043407negative regulation of MAP kinase activityISS
GO:0043507positive regulation of JUN kinase activityIEA
GO:0045080positive regulation of chemokine biosynthetic processIEA
GO:0045086positive regulation of interleukin-2 biosynthetic processIMP
GO:0045410positive regulation of interleukin-6 biosynthetic processIEA
GO:0045429positive regulation of nitric oxide biosynthetic processIDA
GO:0045766positive regulation of angiogenesisIEA
GO:0045766positive regulation of angiogenesisISS
GO:0045833negative regulation of lipid metabolic processIEA
GO:0045833negative regulation of lipid metabolic processISS
GO:0045840positive regulation of mitosisIMP
GO:0045944positive regulation of transcription from RNA polymerase II promoterIEA
GO:0046330positive regulation of JNK cascadeIEA
GO:0046627negative regulation of insulin receptor signaling pathwayIEA
GO:0046627negative regulation of insulin receptor signaling pathwayISS
GO:0046827positive regulation of protein export from nucleusNAS
GO:0050796regulation of insulin secretionIDA
GO:0050900leukocyte migrationIEA
GO:0050995negative regulation of lipid catabolic processIDA
GO:0050996positive regulation of lipid catabolic processIEA
GO:0050996positive regulation of lipid catabolic processISS
GO:0051044positive regulation of membrane protein ectodomain proteolysisIDA
GO:0051091positive regulation of sequence-specific DNA binding transcription factor activityIDA
GO:0051092positive regulation of NF-kappaB transcription factor activityIDA
GO:0051384response to glucocorticoid stimulusIEA
GO:0051781positive regulation of cell divisionIEA
GO:0060355positive regulation of cell adhesion molecule productionNAS
GO:0060559positive regulation of calcidiol 1-monooxygenase activityIDA
GO:0070164negative regulation of adiponectin secretionIEA
GO:0070164negative regulation of adiponectin secretionISS
GO:0070374positive regulation of ERK1 and ERK2 cascadeIEA
GO:0071260cellular response to mechanical stimulusIEP
GO:0071310cellular response to organic substanceIDA
GO:0071639positive regulation of monocyte chemotactic protein-1 productionIDA
cellular_component
GO:0005576extracellular regionIEA
GO:0005576extracellular regionNAS
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIEA
GO:0005615extracellular spaceIMP
GO:0005829cytosolTAS
GO:0030141stored secretory granuleIEA
GO:0031982vesicleIEA
molecular_function
GO:0005125cytokine activityIDA
GO:0005125cytokine activityIEA
GO:0005125cytokine activityIMP
GO:0005149interleukin-1 receptor bindingIEA
GO:0005149interleukin-1 receptor bindingNAS
GO:0008083growth factor activityIEA
GO:0019904protein domain specific bindingIPI

Protein-protein interaction details for IL1B (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
MAPK8IP2Phenotypic Suppressiongenetic10756100
ZNF675Phenotypic Suppressiongenetic11751921
UBE2NPhenotypic Suppressiongenetic11057907
IL1R1Reconstituted Complexphysical7878046