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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IL4 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0002674negative regulation of acute inflammatory responseIEA
GO:0002677negative regulation of chronic inflammatory responseIEA
GO:0006935chemotaxisTAS
GO:0006955immune responseTAS
GO:0006968cellular defense responseTAS
GO:0007565female pregnancyIEA
GO:0007584response to nutrientIEA
GO:0008203cholesterol metabolic processISS
GO:0008284positive regulation of cell proliferationIEA
GO:0010155regulation of proton transportIEA
GO:0014070response to organic cyclic compoundIEA
GO:0030183B cell differentiationTAS
GO:0030890positive regulation of B cell proliferationISS
GO:0032733positive regulation of interleukin-10 productionIEA
GO:0032736positive regulation of interleukin-13 productionIDA
GO:0034097response to cytokine stimulusIEA
GO:0035745T-helper 2 cell cytokine productionIDA
GO:0042092type 2 immune responseTAS
GO:0042102positive regulation of T cell proliferationISS
GO:0042104positive regulation of activated T cell proliferationIEA
GO:0042325regulation of phosphorylationISS
GO:0042493response to drugIEA
GO:0042523positive regulation of tyrosine phosphorylation of Stat5 proteinIEA
GO:0043031negative regulation of macrophage activationIEA
GO:0043066negative regulation of apoptosisISS
GO:0045019negative regulation of nitric oxide biosynthetic processIEA
GO:0045189connective tissue growth factor biosynthetic processTAS
GO:0045191regulation of isotype switchingTAS
GO:0045348positive regulation of MHC class II biosynthetic processISS
GO:0045471response to ethanolIEA
GO:0045582positive regulation of T cell differentiationIDA
GO:0045671negative regulation of osteoclast differentiationISS
GO:0045892negative regulation of transcription, DNA-dependentIDA
GO:0045893positive regulation of transcription, DNA-dependentIDA
GO:0045944positive regulation of transcription from RNA polymerase II promoterISS
GO:0048295positive regulation of isotype switching to IgE isotypesISS
GO:0048304positive regulation of isotype switching to IgG isotypesISS
GO:0050727regulation of inflammatory responseIEA
GO:0050731positive regulation of peptidyl-tyrosine phosphorylationIEA
GO:0050776regulation of immune responseISS
GO:0071288cellular response to mercury ionIEA
cellular_component
GO:0005576extracellular regionIEA
GO:0005615extracellular spaceTAS
molecular_function
GO:0005125cytokine activityIEA
GO:0005136interleukin-4 receptor bindingTAS
GO:0005515protein bindingIPI
GO:0008083growth factor activityNAS

Protein-protein interaction details for IL4 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
IL4RCo-crystal Structurephysical11786020
A2MReconstituted Complexphysical10714547