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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for IL4R (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0002532
production of molecular mediator involved in inflammatory response
IEA
GO:0006955
immune response
TAS
GO:0007165
signal transduction
TAS
GO:0030728
ovulation
IEA
GO:0035771
interleukin-4-mediated signaling pathway
TAS
GO:0042127
regulation of cell proliferation
IEA
GO:0043032
positive regulation of macrophage activation
IEA
GO:0043627
response to estrogen stimulus
IEA
GO:0045626
negative regulation of T-helper 1 cell differentiation
IEA
GO:0045630
positive regulation of T-helper 2 cell differentiation
IEA
GO:0090197
positive regulation of chemokine secretion
IEA
cellular_component
GO:0005576
extracellular region
IEA
GO:0005615
extracellular space
IEA
GO:0005886
plasma membrane
IEA
GO:0005887
integral to plasma membrane
TAS
GO:0016020
membrane
IEA
GO:0016021
integral to membrane
IEA
molecular_function
GO:0004872
receptor activity
IEA
GO:0004896
cytokine receptor activity
IEA
GO:0004913
interleukin-4 receptor activity
TAS
GO:0005057
receptor signaling protein activity
TAS
GO:0005515
protein binding
IPI
GO:0043560
insulin receptor substrate binding
RCA
Protein-protein interaction details for IL4R (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
GNB2L1
Reconstituted Complex
physical
12960323
ARIH2
Two-hybrid
physical
16169070
SHC1
Affinity Capture-Western
physical
10652211
PTPN6
Reconstituted Complex
physical
11714803
INPP5D
Reconstituted Complex
physical
11714803
SHC1
Reconstituted Complex
physical
11714803
PTPN11
Reconstituted Complex
physical
11714803
IL4
Co-crystal Structure
physical
11786020
JAK1
Reconstituted Complex
physical
12133952
NCF1
Affinity Capture-Western
physical
10369419
HGS
Affinity Capture-Western
physical
21362618
HGS
Reconstituted Complex
physical
21362618
UBC
Affinity Capture-Western
physical
21362618