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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for IL10 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002237 response to molecule of bacterial origin IDA GO:0002740 negative regulation of cytokine secretion involved in immune response IDA GO:0002904 positive regulation of B cell apoptosis IDA GO:0006916 anti-apoptosis NAS GO:0006950 response to stress IEA GO:0006954 inflammatory response IDA GO:0007253 cytoplasmic sequestering of NF-kappaB NAS GO:0007267 cell-cell signaling IC GO:0010468 regulation of gene expression IDA GO:0014823 response to activity IEA GO:0030097 hemopoiesis TAS GO:0030183 B cell differentiation NAS GO:0030595 leukocyte chemotaxis TAS GO:0030889 negative regulation of B cell proliferation IDA GO:0032496 response to lipopolysaccharide IEA GO:0032715 negative regulation of interleukin-6 production IDA GO:0032800 receptor biosynthetic process IDA GO:0032868 response to insulin stimulus IEA GO:0034465 response to carbon monoxide IEA GO:0042092 type 2 immune response TAS GO:0042100 B cell proliferation NAS GO:0042130 negative regulation of T cell proliferation NAS GO:0042493 response to drug IEA GO:0042536 negative regulation of tumor necrosis factor biosynthetic process IEA GO:0045019 negative regulation of nitric oxide biosynthetic process IEA GO:0045191 regulation of isotype switching NAS GO:0045347 negative regulation of MHC class II biosynthetic process TAS GO:0045355 negative regulation of interferon-alpha biosynthetic process NAS GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0050715 positive regulation of cytokine secretion IDA GO:0050728 negative regulation of inflammatory response IEA GO:0051045 negative regulation of membrane protein ectodomain proteolysis IDA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity IDA GO:0051384 response to glucocorticoid stimulus IDA GO:0051930 regulation of sensory perception of pain IEA GO:0071392 cellular response to estradiol stimulus IEA cellular_component GO:0005576 extracellular region IEA GO:0005615 extracellular space IDA molecular_function GO:0005125 cytokine activity NAS GO:0005141 interleukin-10 receptor binding NAS GO:0008083 growth factor activity NAS

Protein-protein interaction details for IL10 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID IL10RA Co-purification physical 8248239 IL10RA Co-crystal Structure physical 11485736 IL10RA Reconstituted Complex physical 7759550 A2M Reconstituted Complex physical 10714547 IL10 Co-crystal Structure physical 8590020 IL10RA Reconstituted Complex physical 11717514 IL10RA Co-crystal Structure physical 10231374