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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for IL12A (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001916
positive regulation of T cell mediated cytotoxicity
IDA
GO:0002860
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
IDA
GO:0006955
immune response
IEA
GO:0006955
immune response
TAS
GO:0007050
cell cycle arrest
IDA
GO:0009615
response to virus
IEP
GO:0010224
response to UV-B
IDA
GO:0016477
cell migration
IDA
GO:0032496
response to lipopolysaccharide
IDA
GO:0032700
negative regulation of interleukin-17 production
IDA
GO:0032729
positive regulation of interferon-gamma production
IDA
GO:0032816
positive regulation of natural killer cell activation
IDA
GO:0034393
positive regulation of smooth muscle cell apoptosis
IDA
GO:0042102
positive regulation of T cell proliferation
IEA
GO:0042520
positive regulation of tyrosine phosphorylation of Stat4 protein
IDA
GO:0042832
defense response to protozoan
IEA
GO:0045785
positive regulation of cell adhesion
IDA
GO:0045954
positive regulation of natural killer cell mediated cytotoxicity
IDA
GO:0048662
negative regulation of smooth muscle cell proliferation
IDA
GO:0050671
positive regulation of lymphocyte proliferation
IDA
GO:0050830
defense response to Gram-positive bacterium
IEP
GO:0051135
positive regulation of NK T cell activation
IDA
cellular_component
GO:0005576
extracellular region
IEA
GO:0005615
extracellular space
IDA
GO:0005737
cytoplasm
IEA
GO:0043514
interleukin-12 complex
IDA
GO:0043514
interleukin-12 complex
NAS
molecular_function
GO:0005125
cytokine activity
IDA
GO:0005125
cytokine activity
TAS
GO:0005143
interleukin-12 receptor binding
IEA
GO:0005143
interleukin-12 receptor binding
NAS
GO:0005515
protein binding
IPI
GO:0008083
growth factor activity
IDA
GO:0008083
growth factor activity
IEA
GO:0008083
growth factor activity
NAS
GO:0042163
interleukin-12 beta subunit binding
IEA
GO:0045513
interleukin-27 binding
IPI
GO:0046982
protein heterodimerization activity
IPI
Protein-protein interaction details for IL12A (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
IL12B
Co-crystal Structure
physical
10899108