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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for LRP5 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001702
gastrulation with mouth forming second
IBA
GO:0002053
positive regulation of mesenchymal cell proliferation
IMP
GO:0002076
osteoblast development
IBA
GO:0006007
glucose catabolic process
IMP
GO:0006897
endocytosis
IEA
GO:0007275
multicellular organismal development
IEA
GO:0008217
regulation of blood pressure
IMP
GO:0008284
positive regulation of cell proliferation
IDA
GO:0009952
anterior/posterior pattern specification
IBA
GO:0016055
Wnt receptor signaling pathway
IDA
GO:0030326
embryonic limb morphogenesis
IBA
GO:0042632
cholesterol homeostasis
IMP
GO:0044332
Wnt receptor signaling pathway involved in dorsal/ventral axis specification
IDA
GO:0045600
positive regulation of fat cell differentiation
IMP
GO:0045668
negative regulation of osteoblast differentiation
IMP
GO:0045840
positive regulation of mitosis
IDA
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
GO:0045944
positive regulation of transcription from RNA polymerase II promoter
IDA
GO:0046849
bone remodeling
IBA
GO:0048539
bone marrow development
IMP
GO:0048596
embryonic camera-type eye morphogenesis
IBA
GO:0060042
retina morphogenesis in camera-type eye
IMP
GO:0060059
embryonic retina morphogenesis in camera-type eye
IBA
GO:0060070
canonical Wnt receptor signaling pathway
IDA
GO:0060070
canonical Wnt receptor signaling pathway
IMP
GO:0060349
bone morphogenesis
IMP
GO:0060444
branching involved in mammary gland duct morphogenesis
IBA
GO:0060612
adipose tissue development
IMP
GO:0060828
regulation of canonical Wnt receptor signaling pathway
IMP
GO:0061178
regulation of insulin secretion involved in cellular response to glucose stimulus
IBA
GO:0061304
retinal blood vessel morphogenesis
IMP
GO:0071901
negative regulation of protein serine/threonine kinase activity
IMP
cellular_component
GO:0005783
endoplasmic reticulum
IEA
GO:0005886
plasma membrane
IDA
GO:0016020
membrane
IEA
GO:0016021
integral to membrane
IEA
GO:0043235
receptor complex
IDA
molecular_function
GO:0004872
receptor activity
IEA
GO:0005515
protein binding
IPI
GO:0015026
coreceptor activity
IBA
GO:0017147
Wnt-protein binding
IBA
GO:0019534
toxin transporter activity
IMP
GO:0042813
Wnt-activated receptor activity
IBA
Protein-protein interaction details for LRP5 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
MESDC2
Affinity Capture-Western
physical
12581525
FZD8
Affinity Capture-Western
physical
11448771
AXIN1
Affinity Capture-Western
physical
11336703
AXIN1
Affinity Capture-Western
physical
11336703
AXIN1
Affinity Capture-Western
physical
18632848