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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MCM4 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0000084 S phase of mitotic cell cycle TAS GO:0000216 M/G1 transition of mitotic cell cycle TAS GO:0000278 mitotic cell cycle TAS GO:0006260 DNA replication IEA GO:0006260 DNA replication NAS GO:0006260 DNA replication TAS GO:0006268 DNA unwinding involved in replication IEA GO:0006270 DNA-dependent DNA replication initiation IEA GO:0006271 DNA strand elongation involved in DNA replication TAS cellular_component GO:0005634 nucleus IDA GO:0005634 nucleus NAS GO:0005654 nucleoplasm TAS GO:0005730 nucleolus IDA GO:0042555 MCM complex IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding IEA GO:0003678 DNA helicase activity IEA GO:0003697 single-stranded DNA binding IEA GO:0004003 ATP-dependent DNA helicase activity IDA GO:0004386 helicase activity IEA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0005524 ATP binding NAS GO:0016787 hydrolase activity IEA GO:0017111 nucleoside-triphosphatase activity IEA

Protein-protein interaction details for MCM4 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID CDC7 Two-hybrid physical 12614612 MCM8 Affinity Capture-Western physical 12771218 MCM2 Reconstituted Complex physical 12694531 MCM6 Reconstituted Complex physical 12694531 MCM7 Reconstituted Complex physical 12694531 MCM2 Two-hybrid physical 12614612 MCM2 Two-hybrid physical 12614612 MCM4 Two-hybrid physical 12614612 MCM6 Two-hybrid physical 12614612 MCM6 Two-hybrid physical 12614612 ORC1L Two-hybrid physical 12614612 ORC2L Two-hybrid physical 12614612 ORC3L Two-hybrid physical 12614612 ORC4L Two-hybrid physical 12614612 ORC5L Two-hybrid physical 12614612 ORC6L Two-hybrid physical 12614612 ORC1L Two-hybrid physical 12614612 ORC2L Two-hybrid physical 12614612 ORC3L Two-hybrid physical 12614612 ORC4L Two-hybrid physical 12614612 ORC5L Two-hybrid physical 12614612 ORC6L Two-hybrid physical 12614612 CDC7 Two-hybrid physical 12614612 DBF4 Two-hybrid physical 12614612 RPA1 Two-hybrid physical 12614612 RPA2 Two-hybrid physical 12614612 RPA1 Two-hybrid physical 12614612 MCM2 Co-purification physical 10567526 MCM7 Affinity Capture-Western physical 9099751 MCM5 Affinity Capture-Western physical 11248027 MCM6 Affinity Capture-Western physical 8798650 MCM7 Affinity Capture-Western physical 8798650 MCM2 Affinity Capture-Western physical 8798650 CDK2 Biochemical Activity physical 10748114 MCM6 Affinity Capture-Western physical 12207017 MCM7 Affinity Capture-Western physical 12207017 CDT1 Affinity Capture-MS physical 18162579 CDT1 Reconstituted Complex physical 18162579 ING5 Affinity Capture-Western physical 16387653 USP7 Affinity Capture-MS physical 19615732 HIST1H4A Affinity Capture-MS physical 19862764 HIST1H4A Affinity Capture-Western physical 19862764 TLX2 Two-hybrid physical 20211142 SSRP1 Affinity Capture-Western physical 16902406 SSRP1 Affinity Capture-Western physical 16902406 SUPT16H Affinity Capture-Western physical 16902406 SUPT16H Reconstituted Complex physical 16902406 SSRP1 Reconstituted Complex physical 16902406 MCM2 Affinity Capture-Western physical 16902406 CDC45 Affinity Capture-Western physical 16902406 EMD Affinity Capture-MS physical 17620012 L3MBTL Affinity Capture-Western physical 21149733 HDAC5 Affinity Capture-MS physical 21081666 C6orf167 Affinity Capture-MS physical 21055985 NFKBIL2 Affinity Capture-MS physical 21055985 SSRP1 Affinity Capture-MS physical 21055985 NEDD8 Affinity Capture-MS physical 18274552 UBC Affinity Capture-MS physical 20639865