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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for MTHFD1 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0000105
histidine biosynthetic process
IEA
GO:0006164
purine nucleotide biosynthetic process
IEA
GO:0006730
one-carbon metabolic process
IEA
GO:0006766
vitamin metabolic process
TAS
GO:0006767
water-soluble vitamin metabolic process
TAS
GO:0008652
cellular amino acid biosynthetic process
IEA
GO:0009086
methionine biosynthetic process
IEA
GO:0009396
folic acid-containing compound biosynthetic process
IEA
GO:0046655
folic acid metabolic process
TAS
GO:0055114
oxidation-reduction process
IEA
cellular_component
GO:0005737
cytoplasm
IDA
GO:0005739
mitochondrion
TAS
GO:0005829
cytosol
TAS
molecular_function
GO:0000166
nucleotide binding
IEA
GO:0003824
catalytic activity
IEA
GO:0004329
formate-tetrahydrofolate ligase activity
IEA
GO:0004329
formate-tetrahydrofolate ligase activity
TAS
GO:0004477
methenyltetrahydrofolate cyclohydrolase activity
TAS
GO:0004486
methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity
TAS
GO:0004488
methylenetetrahydrofolate dehydrogenase (NADP+) activity
IEA
GO:0005488
binding
IEA
GO:0005524
ATP binding
IEA
GO:0016491
oxidoreductase activity
IEA
GO:0016787
hydrolase activity
IEA
GO:0016874
ligase activity
IEA
Protein-protein interaction details for MTHFD1 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
TRAF6
Affinity Capture-MS
physical
17353931
MCC
Affinity Capture-MS
physical
17353931
WDR8
Affinity Capture-MS
physical
17353931
UBC
Affinity Capture-MS
physical
16196087
MME
Affinity Capture-MS
physical
17342744
HDAC5
Affinity Capture-MS
physical
21081666
PSMA3
Affinity Capture-MS
physical
22079093