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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MTHFD1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000105histidine biosynthetic processIEA
GO:0006164purine nucleotide biosynthetic processIEA
GO:0006730one-carbon metabolic processIEA
GO:0006766vitamin metabolic processTAS
GO:0006767water-soluble vitamin metabolic processTAS
GO:0008652cellular amino acid biosynthetic processIEA
GO:0009086methionine biosynthetic processIEA
GO:0009396folic acid-containing compound biosynthetic processIEA
GO:0046655folic acid metabolic processTAS
GO:0055114oxidation-reduction processIEA
cellular_component
GO:0005737cytoplasmIDA
GO:0005739mitochondrionTAS
GO:0005829cytosolTAS
molecular_function
GO:0000166nucleotide bindingIEA
GO:0003824catalytic activityIEA
GO:0004329formate-tetrahydrofolate ligase activityIEA
GO:0004329formate-tetrahydrofolate ligase activityTAS
GO:0004477methenyltetrahydrofolate cyclohydrolase activityTAS
GO:0004486methylenetetrahydrofolate dehydrogenase [NAD(P)+] activityTAS
GO:0004488methylenetetrahydrofolate dehydrogenase (NADP+) activityIEA
GO:0005488bindingIEA
GO:0005524ATP bindingIEA
GO:0016491oxidoreductase activityIEA
GO:0016787hydrolase activityIEA
GO:0016874ligase activityIEA

Protein-protein interaction details for MTHFD1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
TRAF6Affinity Capture-MSphysical17353931
MCCAffinity Capture-MSphysical17353931
WDR8Affinity Capture-MSphysical17353931
UBCAffinity Capture-MSphysical16196087
MMEAffinity Capture-MSphysical17342744
HDAC5Affinity Capture-MSphysical21081666
PSMA3Affinity Capture-MSphysical22079093