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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NF2 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001707mesoderm formationIEA
GO:0001953negative regulation of cell-matrix adhesionTAS
GO:0006469negative regulation of protein kinase activityIEA
GO:0007398ectoderm developmentIEA
GO:0008156negative regulation of DNA replicationIMP
GO:0008285negative regulation of cell proliferationIDA
GO:0008285negative regulation of cell proliferationIMP
GO:0014010Schwann cell proliferationIMP
GO:0022408negative regulation of cell-cell adhesionIDA
GO:0030036actin cytoskeleton organizationIMP
GO:0030336negative regulation of cell migrationTAS
GO:0035330regulation of hippo signaling cascadeIMP
GO:0042475odontogenesis of dentine-containing toothIEA
GO:0042518negative regulation of tyrosine phosphorylation of Stat3 proteinIDA
GO:0042524negative regulation of tyrosine phosphorylation of Stat5 proteinIDA
GO:0043409negative regulation of MAPKKK cascadeIEA
GO:0045216cell-cell junction organizationIEA
GO:0046426negative regulation of JAK-STAT cascadeIDA
GO:0051496positive regulation of stress fiber assemblyIMP
GO:0070306lens fiber cell differentiationIEA
cellular_component
GO:0005634nucleusIDA
GO:0005730nucleolusIDA
GO:0005737cytoplasmIDA
GO:0005737cytoplasmIEA
GO:0005769early endosomeIDA
GO:0005856cytoskeletonIEA
GO:0005886plasma membraneIDA
GO:0005912adherens junctionIEA
GO:0019898extrinsic to membraneIEA
GO:0030027lamellipodiumIEA
GO:0031527filopodium membraneIEA
GO:0032154cleavage furrowIEA
GO:0032587ruffle membraneIEA
GO:0048471perinuclear region of cytoplasmIDA
molecular_function
GO:0005488bindingIEA
GO:0005515protein bindingIPI
GO:0008092cytoskeletal protein bindingIEA

Protein-protein interaction details for NF2 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
SGSM3Two-hybridphysical15541357
SGSM3Reconstituted Complexphysical15541357
SGSM3Affinity Capture-Westernphysical15541357
SGSM3Co-localizationphysical15541357
MED28Two-hybridphysical15467741
MED28Affinity Capture-Westernphysical15467741
HGSReconstituted Complexphysical11285248
EZRFar Westernphysical10036239
EZRAffinity Capture-Westernphysical10036239
NF2Co-crystal Structurephysical11856822
SOS1Affinity Capture-Westernphysical10675333
ARHGAP32Affinity Capture-Westernphysical12446789
PXNReconstituted Complexphysical12118253
SLC9A3R1Reconstituted Complexphysical9430655
HGSTwo-hybridphysical10861283
HGSAffinity Capture-Westernphysical10861283
HGSAffinity Capture-Westernphysical10861283
HGSReconstituted Complexphysical10861283
SPTBN1Reconstituted Complexphysical11535133
SPTBN1Affinity Capture-Westernphysical11535133
SPTBN1Two-hybridphysical11535133
SDCBPReconstituted Complexphysical11432873
SDCBPReconstituted Complexphysical11432873
SDCBPTwo-hybridphysical11432873
SCHIP1Reconstituted Complexphysical10669747
SCHIP1Affinity Capture-Westernphysical10669747
SCHIP1Affinity Capture-Westernphysical10669747
VprBPAffinity Capture-MSphysical18332868
DDB1Affinity Capture-MSphysical18332868
VprBPAffinity Capture-Westernphysical18332868
DDB1Affinity Capture-Westernphysical18332868
CUL4AAffinity Capture-Westernphysical18332868
RIT1Affinity Capture-Westernphysical18332868
VprBPReconstituted Complexphysical18332868
VprBPAffinity Capture-Westernphysical18332868
DDB1Affinity Capture-Westernphysical18332868
CUL4AAffinity Capture-Westernphysical18332868
RIT1Affinity Capture-Westernphysical18332868
VprBPReconstituted Complexphysical18332868
UBCAffinity Capture-Westernphysical18332868
AKT1Affinity Capture-Westernphysical17891137
AKT1Affinity Capture-Westernphysical17891137
AKT1Reconstituted Complexphysical17891137
AKT1Reconstituted Complexphysical17891137
AGAP2Reconstituted Complexphysical17891137
CD44Affinity Capture-Westernphysical17891137
EZRReconstituted Complexphysical17891137
UBCReconstituted Complexphysical17891137
UBCAffinity Capture-Westernphysical17891137
AMOTAffinity Capture-MSphysical19615732
PYGO2Reconstituted Complexphysical20937768
WWC1Affinity Capture-Westernphysical21233212
WWC1Affinity Capture-Westernphysical21233212