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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for NF2 (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001707
mesoderm formation
IEA
GO:0001953
negative regulation of cell-matrix adhesion
TAS
GO:0006469
negative regulation of protein kinase activity
IEA
GO:0007398
ectoderm development
IEA
GO:0008156
negative regulation of DNA replication
IMP
GO:0008285
negative regulation of cell proliferation
IDA
GO:0008285
negative regulation of cell proliferation
IMP
GO:0014010
Schwann cell proliferation
IMP
GO:0022408
negative regulation of cell-cell adhesion
IDA
GO:0030036
actin cytoskeleton organization
IMP
GO:0030336
negative regulation of cell migration
TAS
GO:0035330
regulation of hippo signaling cascade
IMP
GO:0042475
odontogenesis of dentine-containing tooth
IEA
GO:0042518
negative regulation of tyrosine phosphorylation of Stat3 protein
IDA
GO:0042524
negative regulation of tyrosine phosphorylation of Stat5 protein
IDA
GO:0043409
negative regulation of MAPKKK cascade
IEA
GO:0045216
cell-cell junction organization
IEA
GO:0046426
negative regulation of JAK-STAT cascade
IDA
GO:0051496
positive regulation of stress fiber assembly
IMP
GO:0070306
lens fiber cell differentiation
IEA
cellular_component
GO:0005634
nucleus
IDA
GO:0005730
nucleolus
IDA
GO:0005737
cytoplasm
IDA
GO:0005737
cytoplasm
IEA
GO:0005769
early endosome
IDA
GO:0005856
cytoskeleton
IEA
GO:0005886
plasma membrane
IDA
GO:0005912
adherens junction
IEA
GO:0019898
extrinsic to membrane
IEA
GO:0030027
lamellipodium
IEA
GO:0031527
filopodium membrane
IEA
GO:0032154
cleavage furrow
IEA
GO:0032587
ruffle membrane
IEA
GO:0048471
perinuclear region of cytoplasm
IDA
molecular_function
GO:0005488
binding
IEA
GO:0005515
protein binding
IPI
GO:0008092
cytoskeletal protein binding
IEA
Protein-protein interaction details for NF2 (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
SGSM3
Two-hybrid
physical
15541357
SGSM3
Reconstituted Complex
physical
15541357
SGSM3
Affinity Capture-Western
physical
15541357
SGSM3
Co-localization
physical
15541357
MED28
Two-hybrid
physical
15467741
MED28
Affinity Capture-Western
physical
15467741
HGS
Reconstituted Complex
physical
11285248
EZR
Far Western
physical
10036239
EZR
Affinity Capture-Western
physical
10036239
NF2
Co-crystal Structure
physical
11856822
SOS1
Affinity Capture-Western
physical
10675333
ARHGAP32
Affinity Capture-Western
physical
12446789
PXN
Reconstituted Complex
physical
12118253
SLC9A3R1
Reconstituted Complex
physical
9430655
HGS
Two-hybrid
physical
10861283
HGS
Affinity Capture-Western
physical
10861283
HGS
Affinity Capture-Western
physical
10861283
HGS
Reconstituted Complex
physical
10861283
SPTBN1
Reconstituted Complex
physical
11535133
SPTBN1
Affinity Capture-Western
physical
11535133
SPTBN1
Two-hybrid
physical
11535133
SDCBP
Reconstituted Complex
physical
11432873
SDCBP
Reconstituted Complex
physical
11432873
SDCBP
Two-hybrid
physical
11432873
SCHIP1
Reconstituted Complex
physical
10669747
SCHIP1
Affinity Capture-Western
physical
10669747
SCHIP1
Affinity Capture-Western
physical
10669747
VprBP
Affinity Capture-MS
physical
18332868
DDB1
Affinity Capture-MS
physical
18332868
VprBP
Affinity Capture-Western
physical
18332868
DDB1
Affinity Capture-Western
physical
18332868
CUL4A
Affinity Capture-Western
physical
18332868
RIT1
Affinity Capture-Western
physical
18332868
VprBP
Reconstituted Complex
physical
18332868
VprBP
Affinity Capture-Western
physical
18332868
DDB1
Affinity Capture-Western
physical
18332868
CUL4A
Affinity Capture-Western
physical
18332868
RIT1
Affinity Capture-Western
physical
18332868
VprBP
Reconstituted Complex
physical
18332868
UBC
Affinity Capture-Western
physical
18332868
AKT1
Affinity Capture-Western
physical
17891137
AKT1
Affinity Capture-Western
physical
17891137
AKT1
Reconstituted Complex
physical
17891137
AKT1
Reconstituted Complex
physical
17891137
AGAP2
Reconstituted Complex
physical
17891137
CD44
Affinity Capture-Western
physical
17891137
EZR
Reconstituted Complex
physical
17891137
UBC
Reconstituted Complex
physical
17891137
UBC
Affinity Capture-Western
physical
17891137
AMOT
Affinity Capture-MS
physical
19615732
PYGO2
Reconstituted Complex
physical
20937768
WWC1
Affinity Capture-Western
physical
21233212
WWC1
Affinity Capture-Western
physical
21233212