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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NOTCH3 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006355regulation of transcription, DNA-dependentIEA
GO:0007219Notch signaling pathwayTAS
GO:0007220Notch receptor processingTAS
GO:0007275multicellular organismal developmentIEA
GO:0010467gene expressionTAS
GO:0030900forebrain developmentIEA
GO:0042246tissue regenerationIEA
GO:0045665negative regulation of neuron differentiationIEA
GO:0048663neuron fate commitmentIEA
GO:0050793regulation of developmental processIEA
cellular_component
GO:0005576extracellular regionTAS
GO:0005634nucleusIEA
GO:0005654nucleoplasmTAS
GO:0005788endoplasmic reticulum lumenTAS
GO:0005796Golgi lumenTAS
GO:0005829cytosolTAS
GO:0005886plasma membraneTAS
GO:0016021integral to membraneIEA
molecular_function
GO:0004872receptor activityIEA
GO:0005509calcium ion bindingIEA
GO:0005515protein bindingIPI

Protein-protein interaction details for NOTCH3 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
SNW1Reconstituted Complexphysical11404076
NOTCH1Phenotypic Suppressiongenetic11404076
DLL1Reconstituted Complexphysical11006133
JAG1Reconstituted Complexphysical11006133
JAG2Reconstituted Complexphysical11006133
MAML1Reconstituted Complexphysical11101851
GSK3BAffinity Capture-Westernphysical21502811
GSK3BAffinity Capture-Westernphysical21502811
STRAPAffinity Capture-Westernphysical21502811
STRAPAffinity Capture-Westernphysical21502811
UBCAffinity Capture-Westernphysical21502811
CSNK2BTwo-hybridphysical21900206