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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NTRK1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0000186activation of MAPKK activityTAS
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayIEA
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathwayTAS
GO:0007190activation of adenylate cyclase activityTAS
GO:0007202activation of phospholipase C activityTAS
GO:0007264small GTPase mediated signal transductionTAS
GO:0007265Ras protein signal transductionTAS
GO:0007275multicellular organismal developmentIEA
GO:0007399nervous system developmentIEA
GO:0030154cell differentiationIEA
GO:0048011nerve growth factor receptor signaling pathwayTAS
GO:0048015phosphatidylinositol-mediated signalingTAS
cellular_component
GO:0005768endosomeTAS
GO:0005886plasma membraneTAS
GO:0005887integral to plasma membraneIEA
GO:0016020membraneIEA
molecular_function
GO:0000166nucleotide bindingIEA
GO:0004714transmembrane receptor protein tyrosine kinase activityIEA
GO:0004872receptor activityIEA
GO:0005030neurotrophin receptor activityIEA
GO:0005524ATP bindingIEA
GO:0043121neurotrophin bindingTAS

Protein-protein interaction details for NTRK1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
ABL1Two-hybridphysical10708759
NGFReconstituted Complexphysical14985763
MATKAffinity Capture-Westernphysical10329710
MATKFar Westernphysical10329710
PLCG1Reconstituted Complexphysical1715690
GRB2Affinity Capture-Westernphysical11733534
CAV1Affinity Capture-Westernphysical9867838
NTF3Reconstituted Complexphysical8621424
SQSTM1Affinity Capture-Westernphysical11244088
NGFReconstituted Complexphysical11729324
SH2B1Two-hybridphysical9856458
SHC1Two-hybridphysical9856458
PLCG1Two-hybridphysical9856458
SH2B2Two-hybridphysical9856458
SH2B2Affinity Capture-Westernphysical9856458
SH2B1Affinity Capture-Westernphysical9856458
SHC1Affinity Capture-Westernphysical8183561
SHC1Two-hybridphysical12446789
ARHGAP32Two-hybridphysical12446789
ARHGAP32Affinity Capture-Westernphysical12446789
ARHGAP32Reconstituted Complexphysical12446789
NGFCo-crystal Structurephysical10490030
FRS2Reconstituted Complexphysical10092678
SHC1Reconstituted Complexphysical10092678
PLCG1Reconstituted Complexphysical10092678
FRS2Two-hybridphysical10092678
ABL1Affinity Capture-Westernphysical10679771
NTRK1Co-crystal Structurephysical10388563
GRB2Reconstituted Complexphysical10748052
RAP1AAffinity Capture-Westernphysical11466412
SHC3Affinity Capture-Westernphysical9507002
SH2B1Two-hybridphysical10708759
PLCG1Two-hybridphysical10708759
SHC1Two-hybridphysical10708759
ABL1Reconstituted Complexphysical10708759
GIPC1Affinity Capture-Westernphysical11251075
RGS19Affinity Capture-Westernphysical11251075
SQSTM1Affinity Capture-Westernphysical12471037
PTPN1Protein-peptidephysical12237455
TRAF6Affinity Capture-Westernphysical18457658
SQSTM1Affinity Capture-Westernphysical18457658
SQSTM1Affinity Capture-Westernphysical18174161
SQSTM1Affinity Capture-Westernphysical18174161
UBCAffinity Capture-Westernphysical16701206
NEDD4Affinity Capture-Westernphysical16701206
NEDD4Biochemical Activityphysical16701206
NEDD4Affinity Capture-Westernphysical16701206
NEDD4Affinity Capture-Westernphysical21332718
NEDD4Biochemical Activityphysical21332718
CBLAffinity Capture-Westernphysical21570973
UBCAffinity Capture-Westernphysical21570973
MYCNAffinity Capture-RNAphysical21123453
PIAS2Affinity Capture-RNAphysical21123453
SP1Affinity Capture-RNAphysical21123453
HSP90AA1Affinity Capture-Westernphysical20663926
HSPA4Affinity Capture-Westernphysical20663926
UBCAffinity Capture-Westernphysical20663926
CDC37Affinity Capture-Westernphysical20663926