Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PDGFA (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001525angiogenesisISS
GO:0001666response to hypoxiaIEA
GO:0001775cell activationTAS
GO:0001942hair follicle developmentISS
GO:0002053positive regulation of mesenchymal cell proliferationISS
GO:0002576platelet degranulationTAS
GO:0007179transforming growth factor beta receptor signaling pathwayIEA
GO:0007267cell-cell signalingTAS
GO:0007596blood coagulationTAS
GO:0008284positive regulation of cell proliferationIDA
GO:0009611response to woundingIDA
GO:0009790embryo developmentTAS
GO:0009887organ morphogenesisISS
GO:0010033response to organic substanceIEA
GO:0010035response to inorganic substanceIEA
GO:0010512negative regulation of phosphatidylinositol biosynthetic processIDA
GO:0010544negative regulation of platelet activationIDA
GO:0014068positive regulation of phosphatidylinositol 3-kinase cascadeIDA
GO:0014910regulation of smooth muscle cell migrationIDA
GO:0030031cell projection assemblyISS
GO:0030036actin cytoskeleton organizationISS
GO:0030168platelet activationTAS
GO:0030335positive regulation of cell migrationIDA
GO:0031954positive regulation of protein autophosphorylationIDA
GO:0032355response to estradiol stimulusIEA
GO:0032526response to retinoic acidIEA
GO:0032956regulation of actin cytoskeleton organizationTAS
GO:0035793positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathwayIDA
GO:0042060wound healingTAS
GO:0042493response to drugIEA
GO:0043406positive regulation of MAP kinase activityIDA
GO:0043410positive regulation of MAPKKK cascadeIMP
GO:0043588skin developmentISS
GO:0045740positive regulation of DNA replicationIDA
GO:0048008platelet-derived growth factor receptor signaling pathwayIDA
GO:0048146positive regulation of fibroblast proliferationIDA
GO:0048286lung alveolus developmentISS
GO:0048839inner ear developmentIEA
GO:0050730regulation of peptidyl-tyrosine phosphorylationISS
GO:0050919negative chemotaxisIDA
GO:0051781positive regulation of cell divisionIEA
GO:0051897positive regulation of protein kinase B signaling cascadeIDA
GO:0060683regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signalingISS
GO:0070374positive regulation of ERK1 and ERK2 cascadeIDA
GO:0072124regulation of glomerular mesangial cell proliferationIDA
GO:2000278regulation of DNA biosynthetic processIDA
cellular_component
GO:0000139Golgi membraneTAS
GO:0005576extracellular regionTAS
GO:0005615extracellular spaceIDA
GO:0005788endoplasmic reticulum lumenTAS
GO:0005902microvillusISS
GO:0009986cell surfaceIDA
GO:0016020membraneIEA
GO:0031093platelet alpha granule lumenTAS
molecular_function
GO:0005161platelet-derived growth factor receptor bindingIDA
GO:0005161platelet-derived growth factor receptor bindingIPI
GO:0005518collagen bindingIDA
GO:0008083growth factor activityIEA
GO:0042803protein homodimerization activityIDA
GO:0043498cell surface bindingIDA
GO:0043499eukaryotic cell surface bindingIDA
GO:0046982protein heterodimerization activityIPI
GO:0048407platelet-derived growth factor bindingIPI

Protein-protein interaction details for PDGFA (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
PDGFRAReconstituted Complexphysical2544881
PLCG1Affinity Capture-Westernphysical8443409
PDAP1Co-purificationphysical8780057
HSPG2Reconstituted Complexphysical9692901