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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for PDGFA (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0001525
angiogenesis
ISS
GO:0001666
response to hypoxia
IEA
GO:0001775
cell activation
TAS
GO:0001942
hair follicle development
ISS
GO:0002053
positive regulation of mesenchymal cell proliferation
ISS
GO:0002576
platelet degranulation
TAS
GO:0007179
transforming growth factor beta receptor signaling pathway
IEA
GO:0007267
cell-cell signaling
TAS
GO:0007596
blood coagulation
TAS
GO:0008284
positive regulation of cell proliferation
IDA
GO:0009611
response to wounding
IDA
GO:0009790
embryo development
TAS
GO:0009887
organ morphogenesis
ISS
GO:0010033
response to organic substance
IEA
GO:0010035
response to inorganic substance
IEA
GO:0010512
negative regulation of phosphatidylinositol biosynthetic process
IDA
GO:0010544
negative regulation of platelet activation
IDA
GO:0014068
positive regulation of phosphatidylinositol 3-kinase cascade
IDA
GO:0014910
regulation of smooth muscle cell migration
IDA
GO:0030031
cell projection assembly
ISS
GO:0030036
actin cytoskeleton organization
ISS
GO:0030168
platelet activation
TAS
GO:0030335
positive regulation of cell migration
IDA
GO:0031954
positive regulation of protein autophosphorylation
IDA
GO:0032355
response to estradiol stimulus
IEA
GO:0032526
response to retinoic acid
IEA
GO:0032956
regulation of actin cytoskeleton organization
TAS
GO:0035793
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
IDA
GO:0042060
wound healing
TAS
GO:0042493
response to drug
IEA
GO:0043406
positive regulation of MAP kinase activity
IDA
GO:0043410
positive regulation of MAPKKK cascade
IMP
GO:0043588
skin development
ISS
GO:0045740
positive regulation of DNA replication
IDA
GO:0048008
platelet-derived growth factor receptor signaling pathway
IDA
GO:0048146
positive regulation of fibroblast proliferation
IDA
GO:0048286
lung alveolus development
ISS
GO:0048839
inner ear development
IEA
GO:0050730
regulation of peptidyl-tyrosine phosphorylation
ISS
GO:0050919
negative chemotaxis
IDA
GO:0051781
positive regulation of cell division
IEA
GO:0051897
positive regulation of protein kinase B signaling cascade
IDA
GO:0060683
regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling
ISS
GO:0070374
positive regulation of ERK1 and ERK2 cascade
IDA
GO:0072124
regulation of glomerular mesangial cell proliferation
IDA
GO:2000278
regulation of DNA biosynthetic process
IDA
cellular_component
GO:0000139
Golgi membrane
TAS
GO:0005576
extracellular region
TAS
GO:0005615
extracellular space
IDA
GO:0005788
endoplasmic reticulum lumen
TAS
GO:0005902
microvillus
ISS
GO:0009986
cell surface
IDA
GO:0016020
membrane
IEA
GO:0031093
platelet alpha granule lumen
TAS
molecular_function
GO:0005161
platelet-derived growth factor receptor binding
IDA
GO:0005161
platelet-derived growth factor receptor binding
IPI
GO:0005518
collagen binding
IDA
GO:0008083
growth factor activity
IEA
GO:0042803
protein homodimerization activity
IDA
GO:0043498
cell surface binding
IDA
GO:0043499
eukaryotic cell surface binding
IDA
GO:0046982
protein heterodimerization activity
IPI
GO:0048407
platelet-derived growth factor binding
IPI
Protein-protein interaction details for PDGFA (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
PDGFRA
Reconstituted Complex
physical
2544881
PLCG1
Affinity Capture-Western
physical
8443409
PDAP1
Co-purification
physical
8780057
HSPG2
Reconstituted Complex
physical
9692901