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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PLCG2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002316 follicular B cell differentiation IEA GO:0007165 signal transduction NAS GO:0007204 elevation of cytosolic calcium ion concentration IEA GO:0007596 blood coagulation TAS GO:0009395 phospholipid catabolic process IEA GO:0010468 regulation of gene expression IEA GO:0016042 lipid catabolic process IEA GO:0030168 platelet activation TAS GO:0032026 response to magnesium ion IEA GO:0032237 activation of store-operated calcium channel activity IEA GO:0032496 response to lipopolysaccharide IEA GO:0032959 inositol trisphosphate biosynthetic process IEA GO:0033198 response to ATP IEA GO:0035556 intracellular signal transduction IEA GO:0043069 negative regulation of programmed cell death IEA GO:0050852 T cell receptor signaling pathway IEA cellular_component GO:0005624 membrane fraction IEA GO:0005886 plasma membrane TAS molecular_function GO:0004435 phosphatidylinositol phospholipase C activity IEA GO:0004629 phospholipase C activity TAS GO:0004871 signal transducer activity IEA GO:0005515 protein binding IPI GO:0016787 hydrolase activity IEA

Protein-protein interaction details for PLCG2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SHC1 Affinity Capture-Western physical 10623845 LYN Affinity Capture-Western physical 8395016 LYN Reconstituted Complex physical 8395016 FYN Reconstituted Complex physical 8395016 BLK Reconstituted Complex physical 8395016 GAB2 Affinity Capture-Western physical 12135708 PTPN11 Affinity Capture-Western physical 12135708 PTPN11 Affinity Capture-Western physical 12135708 GAB2 Affinity Capture-Western physical 12135708 SHC1 Affinity Capture-Western physical 12135708 PRKD1 Affinity Capture-Western physical 8885868 BTK Affinity Capture-Western physical 12093870 CBLB Affinity Capture-Western physical 12093870 LAT2 Affinity Capture-Western physical 12514734 VAV1 Affinity Capture-Western physical 10981967 SYK Affinity Capture-Western physical 10981967 BTK Affinity Capture-Western physical 10981967 LYN Affinity Capture-Western physical 10981967 PLXNB1 Affinity Capture-Western physical 19805522