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Gene
Protein
Transcript
Promoter
Expression
GO/PPI
PubMed
Cross reference
Gene Ontology information for PPM1A (
Homo sapiens
)
(Information is obtained from AmiGO)
ID
Term
Evidence
biological_process
GO:0006470
protein dephosphorylation
IEA
GO:0007050
cell cycle arrest
TAS
GO:0007165
signal transduction
IMP
GO:0008286
insulin receptor signaling pathway
TAS
GO:0010991
negative regulation of SMAD protein complex assembly
IDA
GO:0016055
Wnt receptor signaling pathway
IDA
GO:0016311
dephosphorylation
IDA
GO:0030177
positive regulation of Wnt receptor signaling pathway
IDA
GO:0030512
negative regulation of transforming growth factor beta receptor signaling pathway
IDA
GO:0043123
positive regulation of I-kappaB kinase/NF-kappaB cascade
IMP
GO:0045893
positive regulation of transcription, DNA-dependent
IDA
cellular_component
GO:0005624
membrane fraction
IEA
GO:0005634
nucleus
IDA
GO:0005829
cytosol
TAS
GO:0005891
voltage-gated calcium channel complex
IEA
GO:0008287
protein serine/threonine phosphatase complex
IEA
GO:0043005
neuron projection
IEA
molecular_function
GO:0000287
magnesium ion binding
IEA
GO:0003824
catalytic activity
IEA
GO:0004721
phosphoprotein phosphatase activity
IEA
GO:0004722
protein serine/threonine phosphatase activity
IDA
GO:0004722
protein serine/threonine phosphatase activity
IEA
GO:0004871
signal transducer activity
IMP
GO:0005515
protein binding
IPI
GO:0008022
protein C-terminus binding
IEA
GO:0016787
hydrolase activity
IEA
GO:0030145
manganese ion binding
IEA
GO:0046872
metal ion binding
IEA
GO:0070412
R-SMAD binding
IPI
Protein-protein interaction details for PPM1A (
Homo sapiens
)
(Information is obtained from BioGRID)
Interacting human protein
Experiment
Type
PubMed ID
LXN
Affinity Capture-MS
physical
17353931
GRM3
Two-hybrid
physical
14663150
GRM3
Affinity Capture-Western
physical
14663150