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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PPM1A (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0006470protein dephosphorylationIEA
GO:0007050cell cycle arrestTAS
GO:0007165signal transductionIMP
GO:0008286insulin receptor signaling pathwayTAS
GO:0010991negative regulation of SMAD protein complex assemblyIDA
GO:0016055Wnt receptor signaling pathwayIDA
GO:0016311dephosphorylationIDA
GO:0030177positive regulation of Wnt receptor signaling pathwayIDA
GO:0030512negative regulation of transforming growth factor beta receptor signaling pathwayIDA
GO:0043123positive regulation of I-kappaB kinase/NF-kappaB cascadeIMP
GO:0045893positive regulation of transcription, DNA-dependentIDA
cellular_component
GO:0005624membrane fractionIEA
GO:0005634nucleusIDA
GO:0005829cytosolTAS
GO:0005891voltage-gated calcium channel complexIEA
GO:0008287protein serine/threonine phosphatase complexIEA
GO:0043005neuron projectionIEA
molecular_function
GO:0000287magnesium ion bindingIEA
GO:0003824catalytic activityIEA
GO:0004721phosphoprotein phosphatase activityIEA
GO:0004722protein serine/threonine phosphatase activityIDA
GO:0004722protein serine/threonine phosphatase activityIEA
GO:0004871signal transducer activityIMP
GO:0005515protein bindingIPI
GO:0008022protein C-terminus bindingIEA
GO:0016787hydrolase activityIEA
GO:0030145manganese ion bindingIEA
GO:0046872metal ion bindingIEA
GO:0070412R-SMAD bindingIPI

Protein-protein interaction details for PPM1A (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
LXNAffinity Capture-MSphysical17353931
GRM3Two-hybridphysical14663150
GRM3Affinity Capture-Westernphysical14663150