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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for MASP1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001867 complement activation, lectin pathway IEA GO:0001867 complement activation, lectin pathway IMP GO:0001867 complement activation, lectin pathway TAS GO:0006508 proteolysis IEA GO:0006956 complement activation TAS GO:0045087 innate immune response TAS GO:0045916 negative regulation of complement activation IDA cellular_component GO:0005576 extracellular region TAS GO:0005615 extracellular space IDA GO:0005615 extracellular space IEA molecular_function GO:0004252 serine-type endopeptidase activity IDA GO:0004252 serine-type endopeptidase activity IEA GO:0005509 calcium ion binding IDA GO:0005509 calcium ion binding IEA GO:0005515 protein binding IPI GO:0008233 peptidase activity IDA GO:0008233 peptidase activity IEA GO:0042803 protein homodimerization activity IPI GO:0048306 calcium-dependent protein binding IPI

Protein-protein interaction details for MASP1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MBL2 Affinity Capture-Western physical 10878362 MASP2 Affinity Capture-Western physical 10878362 SERPING1 Reconstituted Complex physical 10946292 FCN2 Reconstituted Complex physical 12421953 MAPK8IP2 Two-hybrid physical 21900206 NUDT21 Two-hybrid physical 21900206 GSK3B Two-hybrid physical 21900206 UFD1L Two-hybrid physical 21900206 RPS6KA3 Two-hybrid physical 21900206 NCK2 Two-hybrid physical 21900206 H2AFX Two-hybrid physical 21900206 MAPK6 Two-hybrid physical 21900206 RPS6KA6 Two-hybrid physical 21900206 GADD45A Two-hybrid physical 21900206