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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PSMC3 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000082 G1/S transition of mitotic cell cycle TAS GO:0000084 S phase of mitotic cell cycle TAS GO:0000209 protein polyubiquitination TAS GO:0000216 M/G1 transition of mitotic cell cycle TAS GO:0000278 mitotic cell cycle TAS GO:0001824 blastocyst development IEA GO:0002474 antigen processing and presentation of peptide antigen via MHC class I TAS GO:0006521 regulation of cellular amino acid metabolic process TAS GO:0006915 apoptosis TAS GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS GO:0016032 viral reproduction TAS GO:0016070 RNA metabolic process TAS GO:0016071 mRNA metabolic process TAS GO:0030163 protein catabolic process IEA GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0034641 cellular nitrogen compound metabolic process TAS GO:0042981 regulation of apoptosis TAS GO:0044419 interspecies interaction between organisms IEA GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS cellular_component GO:0000502 proteasome complex IEA GO:0005634 nucleus IDA GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0003713 transcription coactivator activity TAS GO:0003714 transcription corepressor activity TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016787 hydrolase activity IEA GO:0017111 nucleoside-triphosphatase activity IEA

Protein-protein interaction details for PSMC3 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TXNRD2 Two-hybrid physical 11463857 PSMD13 Affinity Capture-MS physical 17353931 PSMD10 Affinity Capture-MS physical 17353931 PSMD6 Affinity Capture-MS physical 17353931 PAAF1 Affinity Capture-MS physical 17353931 PSMC4 Affinity Capture-MS physical 17353931 HTR1E Affinity Capture-MS physical 17353931 TRAF6 Affinity Capture-MS physical 14743216 VHL Two-hybrid physical 14556007 VHL Affinity Capture-Western physical 14556007 VHL Affinity Capture-Western physical 14556007 HIF1A Affinity Capture-Western physical 14556007 EPAS1 Affinity Capture-Western physical 14556007 STX11 Two-hybrid physical 16169070 TXNRD2 Affinity Capture-Western physical 11463857 TXNRD2 Reconstituted Complex physical 11463857 PSMC5 Reconstituted Complex physical 11463857 PSMC5 Two-hybrid physical 11463857 CDKN2A Affinity Capture-Western physical 17334400 CDKN2A Affinity Capture-Western physical 17334400 PSMD7 Affinity Capture-MS physical 19615732 UCHL5 Affinity Capture-MS physical 19615732 USP14 Affinity Capture-MS physical 19615732 PMS2 Affinity Capture-MS physical 17148452 UBC Affinity Capture-MS physical 16335966 RNF185 Affinity Capture-MS physical 17558393 UBC Affinity Capture-MS physical 16196087 MDM2 Affinity Capture-Western physical 20479273 MDM2 Reconstituted Complex physical 20479273 MDM2 Co-fractionation physical 20479273 MYC Affinity Capture-MS physical 17314511 JKAMP Affinity Capture-Western physical 19269966 MDM2 Affinity Capture-Western physical 20479273 TP53 Affinity Capture-Western physical 20479273 INSIG2 Reconstituted Complex physical 19815544 INSIG1 Reconstituted Complex physical 19815544 UBD Affinity Capture-Western physical 22072791 CIITA Affinity Capture-Western physical 20351748 PSMA3 Affinity Capture-MS physical 22079093 UBC Affinity Capture-MS physical 22118674 SHFM1 Affinity Capture-MS physical 16239144 UBC Affinity Capture-MS physical 18781797 UBC Affinity Capture-MS physical 21987572 MAP3K5 Affinity Capture-Western physical 20843792