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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for PTPRC (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001915 negative regulation of T cell mediated cytotoxicity ISS GO:0001960 negative regulation of cytokine-mediated signaling pathway ISS GO:0002378 immunoglobulin biosynthetic process IMP GO:0006469 negative regulation of protein kinase activity IDA GO:0006469 negative regulation of protein kinase activity ISS GO:0006470 protein dephosphorylation ISS GO:0007166 cell surface receptor linked signaling pathway TAS GO:0007411 axon guidance TAS GO:0010332 response to gamma radiation IEA GO:0016311 dephosphorylation ISS GO:0030217 T cell differentiation ISS GO:0030890 positive regulation of B cell proliferation IMP GO:0033261 regulation of S phase IMP GO:0035335 peptidyl-tyrosine dephosphorylation IDA GO:0042100 B cell proliferation ISS GO:0042102 positive regulation of T cell proliferation ISS GO:0045860 positive regulation of protein kinase activity NAS GO:0050852 T cell receptor signaling pathway IDA GO:0050852 T cell receptor signaling pathway TAS GO:0050853 B cell receptor signaling pathway ISS GO:0050857 positive regulation of antigen receptor-mediated signaling pathway ISS GO:0051209 release of sequestered calcium ion into cytosol ISS GO:0051607 defense response to virus ISS GO:0051726 regulation of cell cycle ISS cellular_component GO:0005886 plasma membrane TAS GO:0005887 integral to plasma membrane IEA GO:0005887 integral to plasma membrane ISS GO:0005925 focal adhesion ISS GO:0009986 cell surface IEA GO:0045121 membrane raft IEA molecular_function GO:0004725 protein tyrosine phosphatase activity IDA GO:0004725 protein tyrosine phosphatase activity IEA GO:0004872 receptor activity IEA GO:0005001 transmembrane receptor protein tyrosine phosphatase activity TAS GO:0005515 protein binding IPI GO:0016787 hydrolase activity IEA GO:0019901 protein kinase binding IPI

Protein-protein interaction details for PTPRC (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID SKAP1 Two-hybrid physical 11909961 PAEP Co-localization physical 12556471 GANAB Affinity Capture-Western physical 9148925 GANAB Reconstituted Complex physical 9148925 PRKCSH Affinity Capture-Western physical 9148925 LCK Affinity Capture-Western physical 8473339 PTPRCAP Reconstituted Complex physical 8537410 CD2 Reconstituted Complex physical 1970422 PLK3 Affinity Capture-Western physical 11551930 LCK Reconstituted Complex physical 8576115 CD8A FRET physical 1834739 CD4 FRET physical 1834739 GANAB Affinity Capture-Western physical 10921916 CD247 Reconstituted Complex physical 7526385 GANAB Affinity Capture-Western physical 11564800 GANAB Reconstituted Complex physical 11564800 CD22 Affinity Capture-Western physical 10228003 SEMA4D Affinity Capture-Western physical 8955171 SLAMF1 Affinity Capture-Western physical 10229804 CD44 Co-fractionation physical 9573028 LYN Affinity Capture-Western physical 7516335 LYN Reconstituted Complex physical 7516335 CD79A Affinity Capture-Western physical 7516335 CD79B Affinity Capture-Western physical 7516335 SKAP1 Affinity Capture-Western physical 11909961 CD1D Affinity Capture-Western physical 10473580 LGALS1 Affinity Capture-Western physical 10490978 LCK Affinity Capture-Western physical 15085197 UBC Reconstituted Complex physical 19850743 UHRF2 Far Western physical 21952639