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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for NLRC4 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0002218 activation of innate immune response TAS GO:0006919 activation of caspase activity IDA GO:0016045 detection of bacterium IDA GO:0042742 defense response to bacterium IDA GO:0043065 positive regulation of apoptosis IMP GO:0045087 innate immune response TAS GO:0050702 interleukin-1 beta secretion IDA cellular_component GO:0005622 intracellular NAS GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0000287 magnesium ion binding TAS GO:0005515 protein binding IPI GO:0005524 ATP binding IDA GO:0042803 protein homodimerization activity IDA

Protein-protein interaction details for NLRC4 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID NLRC4 Affinity Capture-Western physical 15107016 NOD2 Affinity Capture-Western physical 15107016 NA Affinity Capture-Western physical 15107016 NOD1 Affinity Capture-Western physical 15107016 NAIP Affinity Capture-Western physical 15107016 NLRP3 Affinity Capture-Western physical 15107016 CASP1 Affinity Capture-Western physical 15107016 NLRP1 Affinity Capture-Western physical 11472070 BCL10 Affinity Capture-Western physical 11472070 NLRC4 Affinity Capture-Western physical 11472070 CASP1 Affinity Capture-Western physical 11472070 NOD2 Affinity Capture-Western physical 11472070 PYCARD Two-hybrid physical 11374873 NLRC4 Affinity Capture-Western physical 20085538 PSMC5 Affinity Capture-Western physical 20085538 PSMC5 Two-hybrid physical 20085538 PSMC5 Reconstituted Complex physical 20085538 PSMC5 Affinity Capture-Western physical 20085538 CASP8 Affinity Capture-Western physical 20085538 UBC Affinity Capture-Western physical 20085538