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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for UPF1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IDA GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IMP GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay NAS GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS GO:0006260 DNA replication IMP GO:0006281 DNA repair IDA GO:0006406 mRNA export from nucleus TAS GO:0006449 regulation of translational termination IMP GO:0006449 regulation of translational termination NAS GO:0007049 cell cycle IMP GO:0016070 RNA metabolic process TAS GO:0016071 mRNA metabolic process TAS GO:0071044 histone mRNA catabolic process IMP cellular_component GO:0000785 chromatin IDA GO:0000932 cytoplasmic mRNA processing body IEA GO:0005737 cytoplasm NAS GO:0005829 cytosol TAS GO:0035145 exon-exon junction complex IDA molecular_function GO:0000166 nucleotide binding IEA GO:0003677 DNA binding IEA GO:0003682 chromatin binding IDA GO:0003723 RNA binding NAS GO:0004004 ATP-dependent RNA helicase activity IDA GO:0004386 helicase activity NAS GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0008270 zinc ion binding IEA GO:0016787 hydrolase activity IEA GO:0046872 metal ion binding IEA

Protein-protein interaction details for UPF1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID HIRA Two-hybrid physical 15231747 NAA38 Two-hybrid physical 15231747 UPF2 Affinity Capture-Western physical 14527413 UPF3B Affinity Capture-Western physical 14527413 DCP2 Affinity Capture-Western physical 14527413 XRN1 Affinity Capture-Western physical 14527413 EXOSC2 Affinity Capture-Western physical 14527413 EXOSC4 Affinity Capture-Western physical 14527413 PARN Affinity Capture-Western physical 14527413 EXOSC10 Affinity Capture-Western physical 14527413 UPF2 Affinity Capture-MS physical 12723973 PABPC1 Affinity Capture-MS physical 12723973 UPF2 Affinity Capture-Western physical 12723973 UPF3A Affinity Capture-Western physical 12723973 UPF3B Affinity Capture-Western physical 12723973 UPF2 Affinity Capture-Western physical 11073994 SMG1 Biochemical Activity physical 11544179 SMG1 Protein-peptide physical 11544179 SMG1 Affinity Capture-Western physical 11544179 UPF2 Affinity Capture-Western physical 11544179 UPF3A Affinity Capture-Western physical 11544179 DCP1A Affinity Capture-Western physical 12417715 DCP2 Affinity Capture-Western physical 12417715 DCP1A Affinity Capture-Western physical 12417715 DCP2 Affinity Capture-Western physical 12417715 UPF3A Affinity Capture-Western physical 11163187 UPF3B Affinity Capture-Western physical 11163187 UPF2 Affinity Capture-Western physical 11163187 UPF2 Affinity Capture-Western physical 11163187 UPF3B Affinity Capture-Western physical 11163187 ATR Biochemical Activity physical 16488880 UPF2 Affinity Capture-Western physical 16488880 POLD1 Affinity Capture-Western physical 16488880 POLD1 Affinity Capture-Western physical 16488880 UPF2 Affinity Capture-Western physical 16488880 UPF2 Affinity Capture-Western physical 16086026 SLBP Affinity Capture-Western physical 16086026 SLBP Affinity Capture-Western physical 16086026 HDAC5 Affinity Capture-MS physical 21081666 CSNK2B Two-hybrid physical 21900206 UBC Affinity Capture-MS physical 18781797