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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for BCR (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0006468 protein phosphorylation IEA GO:0007165 signal transduction IEA GO:0007165 signal transduction TAS GO:0007264 small GTPase mediated signal transduction TAS GO:0007420 brain development IEA GO:0030036 actin cytoskeleton organization IEA GO:0030336 negative regulation of cell migration IEA GO:0032496 response to lipopolysaccharide IEA GO:0035023 regulation of Rho protein signal transduction IEA GO:0042472 inner ear morphogenesis IEA GO:0043314 negative regulation of neutrophil degranulation IEA GO:0043547 positive regulation of GTPase activity TAS GO:0050728 negative regulation of inflammatory response IEA GO:0050766 positive regulation of phagocytosis IEA GO:0050885 neuromuscular process controlling balance IEA GO:0051056 regulation of small GTPase mediated signal transduction TAS GO:0051726 regulation of cell cycle IEA cellular_component GO:0005622 intracellular IEA GO:0005829 cytosol TAS GO:0005886 plasma membrane IEA molecular_function GO:0000166 nucleotide binding IEA GO:0004674 protein serine/threonine kinase activity IEA GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005089 Rho guanyl-nucleotide exchange factor activity IEA GO:0005096 GTPase activator activity IEA GO:0005524 ATP binding IEA GO:0016301 kinase activity IEA GO:0016740 transferase activity IEA GO:0030675 Rac GTPase activator activity IEA

Protein-protein interaction details for BCR (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID MLLT4 Two-hybrid physical 12808105 HCK Affinity Capture-Western physical 12592324 PTPN6 Affinity Capture-Western physical 9788431 PTPN6 Affinity Capture-Western physical 9788431 FES Affinity Capture-Western physical 10706130 FES Affinity Capture-Western physical 10706130 RB1 Affinity Capture-Western physical 9071815 ERCC3 Far Western physical 9874796 GRB2 Affinity Capture-Western physical 10887132 CRKL Two-hybrid physical 9747873 GRB2 Two-hybrid physical 9747873 PIK3CG Two-hybrid physical 9747873 GRB10 Two-hybrid physical 9747873 GRB10 Affinity Capture-Western physical 9747873 ABL1 Affinity Capture-Western physical 12543778 ABL1 Reconstituted Complex physical 1712671 GAB2 Affinity Capture-Western physical 15143164 HCK Affinity Capture-Western physical 10849448 HOXA9 Phenotypic Enhancement genetic 12393433 CRKL Affinity Capture-Western physical 8978305 CRKL Two-hybrid physical 8978305 CBL Co-purification physical 8641358 PIK3CG Co-purification physical 8641358 PXN Co-purification physical 8641358 TLN1 Co-purification physical 8641358 CRKL Two-hybrid physical 10194128 CRKL Far Western physical 10194128 GRB2 Affinity Capture-Western physical 15143164 GRB2 Far Western physical 15143164 CRKL Affinity Capture-Western physical 15143164 KIT Affinity Capture-Western physical 8757502 KIT Affinity Capture-Western physical 8757502 ERCC3 Two-hybrid physical 9874796 GRB10 Reconstituted Complex physical 9747873 PIK3CG Affinity Capture-Western physical 7606002 MLLT4 Affinity Capture-Western physical 12808105 MLLT4 Reconstituted Complex physical 12808105 MLLT4 Biochemical Activity physical 12808105 IGSF21 Two-hybrid physical 16169070 TP53 Two-hybrid physical 16169070 UNC119 Two-hybrid physical 16169070 ABL1 Affinity Capture-Western physical 8112292 GRB2 Affinity Capture-Western physical 8112292 GRB2 Reconstituted Complex physical 8112292 ABL1 Reconstituted Complex physical 8112292 SOS1 Affinity Capture-Western physical 8112292 GRB2 Affinity Capture-Western physical 9178913 PXN Affinity Capture-Western physical 7534286 RAC1 Reconstituted Complex physical 9535855 CDC42 Reconstituted Complex physical 9535855 RHOA Reconstituted Complex physical 9535855 FES Affinity Capture-Western physical 7529874 FES Reconstituted Complex physical 7529874 GRB2 Affinity Capture-Western physical 7529874 SOS1 Affinity Capture-Western physical 7529874 GRB2 Reconstituted Complex physical 7529874 IL3 Affinity Capture-Western physical 9209414 WDR48 Affinity Capture-MS physical 19615732 ERCC3 Affinity Capture-MS physical 17643375 TSG101 Affinity Capture-Western physical 16778200 TSG101 Two-hybrid physical 16778200 VPS28 Affinity Capture-Western physical 16778200 TSG101 Reconstituted Complex physical 16778200 INPP5D Affinity Capture-Western physical 20304029 MYC Affinity Capture-MS physical 17314511 HSP90AA1 Affinity Capture-Western physical 21248063 UBC Reconstituted Complex physical 20675402 STUB1 Biochemical Activity physical 20675402 CBL Biochemical Activity physical 20675402 HSPA8 Reconstituted Complex physical 20675402 HSPA8 Affinity Capture-Western physical 20675402 HSP90AA1 Affinity Capture-Western physical 20675402