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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TIMP1 (Homo sapiens)
(Information is obtained from AmiGO)
IDTermEvidence
biological_process
GO:0001775cell activationIEA
GO:0002576platelet degranulationTAS
GO:0007568agingIEA
GO:0007596blood coagulationTAS
GO:0008284positive regulation of cell proliferationTAS
GO:0030168platelet activationTAS
GO:0034097response to cytokine stimulusIEA
GO:0042060wound healingIEA
GO:0043066negative regulation of apoptosisIEA
GO:0043249erythrocyte maturationIEA
GO:0043434response to peptide hormone stimulusIEA
GO:0051045negative regulation of membrane protein ectodomain proteolysisIDA
cellular_component
GO:0005576extracellular regionNAS
GO:0005576extracellular regionTAS
GO:0005604basement membraneIEA
GO:0031093platelet alpha granule lumenTAS
molecular_function
GO:0004857enzyme inhibitor activityIEA
GO:0005515protein bindingIPI
GO:0008191metalloendopeptidase inhibitor activityIDA
GO:0008191metalloendopeptidase inhibitor activityIEA
GO:0046872metal ion bindingIEA

Protein-protein interaction details for TIMP1 (Homo sapiens)
(Information is obtained from BioGRID)
Interacting human proteinExperimentTypePubMed ID
RECQL5Two-hybridphysical16169070
ECH1Two-hybridphysical16169070
EEF1B2Two-hybridphysical16169070
MMP3Co-crystal Structurephysical9288970
MMP1Reconstituted Complexphysical9063449
UBCAffinity Capture-MSphysical21987572