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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TPM1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001701 in utero embryonic development IEA GO:0003065 positive regulation of heart rate by epinephrine IEA GO:0003065 positive regulation of heart rate by epinephrine ISS GO:0006928 cellular component movement TAS GO:0006936 muscle contraction TAS GO:0006937 regulation of muscle contraction TAS GO:0007010 cytoskeleton organization TAS GO:0008016 regulation of heart contraction TAS GO:0009790 embryo development IEA GO:0030049 muscle filament sliding ISS GO:0030049 muscle filament sliding TAS GO:0030336 negative regulation of cell migration ISS GO:0031529 ruffle organization ISS GO:0032781 positive regulation of ATPase activity ISS GO:0034614 cellular response to reactive oxygen species IEP GO:0042060 wound healing ISS GO:0045214 sarcomere organization IMP GO:0045785 positive regulation of cell adhesion ISS GO:0051496 positive regulation of stress fiber assembly ISS GO:0055010 ventricular cardiac muscle tissue morphogenesis IEA GO:0055010 ventricular cardiac muscle tissue morphogenesis IMP GO:0060048 cardiac muscle contraction IEA GO:0060048 cardiac muscle contraction IMP cellular_component GO:0001725 stress fiber IDA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005829 cytosol TAS GO:0005856 cytoskeleton TAS GO:0005862 muscle thin filament tropomyosin TAS GO:0015629 actin cytoskeleton IDA GO:0030016 myofibril IEA GO:0030017 sarcomere TAS GO:0031941 filamentous actin IEA GO:0032059 bleb IMP GO:0032587 ruffle membrane IDA molecular_function GO:0003779 actin binding TAS GO:0005200 structural constituent of cytoskeleton TAS GO:0008307 structural constituent of muscle TAS

Protein-protein interaction details for TPM1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID C19orf50 Two-hybrid physical 16189514 TNNT1 Reconstituted Complex physical 6822572 CNN1 Reconstituted Complex physical 2161834 TPM1 Affinity Capture-Western physical 7568216 TNNT2 Reconstituted Complex physical 6746613 TPM1 Reconstituted Complex physical 3857586 TPM2 Reconstituted Complex physical 3857586 TPM2 Reconstituted Complex physical 3857586 EGFR PCA physical 20029029 CNN1 Co-purification physical 2455687 YWHAQ Affinity Capture-MS physical 20618440 UBC Affinity Capture-MS physical 22178446