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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for UBE2D1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000075 cell cycle checkpoint TAS GO:0000209 protein polyubiquitination IDA GO:0000278 mitotic cell cycle TAS GO:0006511 ubiquitin-dependent protein catabolic process IDA GO:0007094 mitotic cell cycle spindle assembly checkpoint TAS GO:0007179 transforming growth factor beta receptor signaling pathway TAS GO:0030509 BMP signaling pathway TAS GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process TAS GO:0031398 positive regulation of protein ubiquitination IDA GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle TAS GO:0070936 protein K48-linked ubiquitination IDA cellular_component GO:0005654 nucleoplasm TAS GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS molecular_function GO:0000166 nucleotide binding IEA GO:0004842 ubiquitin-protein ligase activity IDA GO:0005515 protein binding IPI GO:0005524 ATP binding IEA GO:0016874 ligase activity IEA GO:0016881 acid-amino acid ligase activity IEA

Protein-protein interaction details for UBE2D1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TRIM39 Two-hybrid physical 16189514 RNF126 Two-hybrid physical 16189514 BARD1 Reconstituted Complex physical 12485996 BRCA1 Reconstituted Complex physical 12485996 BRCA1 Reconstituted Complex physical 12732733 BRCA1 Reconstituted Complex physical 14638690 BARD1 Reconstituted Complex physical 12438698 BRCA1 Reconstituted Complex physical 12438698 BARD1 Reconstituted Complex physical 11927591 BRCA1 Reconstituted Complex physical 11927591 BARD1 Reconstituted Complex physical 14636569 BARD1 Reconstituted Complex physical 12890688 BARD1 Reconstituted Complex physical 11278247 BRCA1 Reconstituted Complex physical 14636569 BRCA1 Reconstituted Complex physical 12890688 BRCA1 Reconstituted Complex physical 11278247 BRE Reconstituted Complex physical 14636569 BRCC3 Reconstituted Complex physical 14636569 DTX3L Affinity Capture-Western physical 12670957 UBE3A Biochemical Activity physical 8576257 RNF2 Biochemical Activity physical 11513855 MDM4 Reconstituted Complex physical 12393902 SIAH1 Two-hybrid physical 11389839 UBE3A Biochemical Activity physical 10066826 TOPORS Reconstituted Complex physical 19053840 TOPORS Affinity Capture-Western physical 19053840 NFKBIA Two-hybrid physical 9409737 CBL Reconstituted Complex physical 18508924 STUB1 Reconstituted Complex physical 18485199 STUB1 Reconstituted Complex physical 17873020 DDX58 Biochemical Activity physical 17719635 STAM2 Biochemical Activity physical 17588522 EPS15 Biochemical Activity physical 17588522 POLM Biochemical Activity physical 17588522 POLL Biochemical Activity physical 17588522 HDAC6 Biochemical Activity physical 17588522 UBASH3B Biochemical Activity physical 17588522 NHLRC1 Co-localization physical 17337485 EPM2A Co-localization physical 17337485 Ufm1 Two-hybrid physical 19690564 AMFR Two-hybrid physical 19690564 MUL1 Two-hybrid physical 19690564 CADPS2 Two-hybrid physical 19690564 DTX1 Two-hybrid physical 19690564 UBE4A Two-hybrid physical 19690564 RNF103 Two-hybrid physical 19690564 RNF181 Two-hybrid physical 19690564 MAP3K1 Two-hybrid physical 19690564 MIB1 Two-hybrid physical 19690564 PJA2 Two-hybrid physical 19690564 RFWD3 Two-hybrid physical 19690564 RNF11 Two-hybrid physical 19690564 RNF111 Two-hybrid physical 19690564 RNF13 Two-hybrid physical 19690564 RNF130 Two-hybrid physical 19690564 RNF150 Two-hybrid physical 19690564 RNF165 Two-hybrid physical 19690564 RNF167 Two-hybrid physical 19690564 RNF25 Two-hybrid physical 19690564 RNF43 Two-hybrid physical 19690564 RNF4 Two-hybrid physical 19690564 TOPORS Two-hybrid physical 19690564 RNF115 Two-hybrid physical 19690564 ZNRF1 Two-hybrid physical 19690564 ZNRF2 Two-hybrid physical 19690564 ZNRF4 Two-hybrid physical 19690564 XIAP Two-hybrid physical 19549727 RNF125 Two-hybrid physical 19549727 RNF126 Two-hybrid physical 19549727 UBOX5 Two-hybrid physical 19549727 RNF5 Two-hybrid physical 19549727 DTX3 Two-hybrid physical 19549727 RNF14 Two-hybrid physical 19549727 ZNRF1 Two-hybrid physical 19549727 RNF114 Two-hybrid physical 19549727 RNF11 Two-hybrid physical 19549727 TRIM8 Two-hybrid physical 19549727 DTX3L Two-hybrid physical 19549727 DZIP3 Two-hybrid physical 19549727 MID1 Two-hybrid physical 19549727 MKRN3 Two-hybrid physical 19549727 TRIM39 Two-hybrid physical 19549727 TRIM27 Two-hybrid physical 19549727 RNF10 Two-hybrid physical 19549727 RNF111 Two-hybrid physical 19549727 RNF166 Two-hybrid physical 19549727 RNF185 Two-hybrid physical 19549727 RNF2 Two-hybrid physical 19549727 RNF25 Two-hybrid physical 19549727 TRIM43 Two-hybrid physical 19549727 TRAF6 Two-hybrid physical 19549727 BIRC8 Two-hybrid physical 19549727 BFAR Two-hybrid physical 19549727 RNF4 Two-hybrid physical 19549727 TRAF7 Two-hybrid physical 19549727 RING1 Two-hybrid physical 19549727 RLIM Two-hybrid physical 19549727 LRSAM1 Two-hybrid physical 19549727 AMFR Two-hybrid physical 19549727 SIAH1 Two-hybrid physical 19549727 CHFR Two-hybrid physical 19549727 ARIH2 Two-hybrid physical 19549727 MGRN1 Two-hybrid physical 19549727 TRIM55 Two-hybrid physical 19549727 RFWD3 Two-hybrid physical 19549727 RNF38 Two-hybrid physical 19549727 RNF7 Two-hybrid physical 19549727 TRIM17 Two-hybrid physical 19549727 TRIM2 Two-hybrid physical 19549727 TRIM25 Two-hybrid physical 19549727 TRIM26 Two-hybrid physical 19549727 TRIM31 Two-hybrid physical 19549727 TRIM35 Two-hybrid physical 19549727 TRIM5 Two-hybrid physical 19549727 RNF11 Reconstituted Complex physical 14562029 BIRC2 Affinity Capture-Western physical 12525502 BIRC3 Affinity Capture-Western physical 12525502 XIAP Affinity Capture-Western physical 12525502 UBC Reconstituted Complex physical 11752173 STUB1 Reconstituted Complex physical 11557750 MDM2 Two-hybrid physical 17301054 UBC Co-crystal Structure physical 17218787 RNF4 Affinity Capture-MS physical 21857666 RNF4 Reconstituted Complex physical 21857666 CUL2 Reconstituted Complex physical 17132228 CUL2 Affinity Capture-Western physical 17132228 UBC Co-crystal Structure physical 21396940 BIRC2 Two-hybrid physical 21113135 BIRC3 Two-hybrid physical 21113135 BIRC7 Two-hybrid physical 21113135 XIAP Two-hybrid physical 21113135 STUB1 Reconstituted Complex physical 20146531 MID1 Biochemical Activity physical 21296087 UBC Reconstituted Complex physical 20347421 BTRC Affinity Capture-Western physical 20378537 UBC Affinity Capture-Western physical 20378537 MYLIP Co-crystal Structure physical 21685362 OTUB1 Affinity Capture-Western physical 22124327 MKNK1 Two-hybrid physical 21900206 GSK3B Two-hybrid physical 21900206 C7orf25 Two-hybrid physical 21900206 TAF1D Two-hybrid physical 21900206 ANXA1 Two-hybrid physical 21900206 CDKN1A Two-hybrid physical 21900206 TNNT1 Two-hybrid physical 21900206 SIRT6 Two-hybrid physical 21900206 HSD17B10 Two-hybrid physical 21900206 NR1H2 Two-hybrid physical 21900206 ANXA7 Two-hybrid physical 21900206 TSC22D1 Two-hybrid physical 21900206 GADD45A Two-hybrid physical 21900206 STUB1 Reconstituted Complex physical 21518764 BRCA1 Two-hybrid physical 19712108 BRCA1 Co-crystal Structure physical 19712108 BRCA1 Reconstituted Complex physical 19712108