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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for WT1 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000122 negative regulation of transcription from RNA polymerase II promoter IDA GO:0001570 vasculogenesis ISS GO:0001657 ureteric bud development ISS GO:0001658 branching involved in ureteric bud morphogenesis IGI GO:0001822 kidney development IGI GO:0003156 regulation of organ formation ISS GO:0006351 transcription, DNA-dependent ISS GO:0006351 transcription, DNA-dependent NAS GO:0006355 regulation of transcription, DNA-dependent ISS GO:0006355 regulation of transcription, DNA-dependent NAS GO:0006357 regulation of transcription from RNA polymerase II promoter ISS GO:0006917 induction of apoptosis IDA GO:0007281 germ cell development ISS GO:0007356 thorax and anterior abdomen determination ISS GO:0007507 heart development IGI GO:0007530 sex determination IDA GO:0008285 negative regulation of cell proliferation IDA GO:0008380 RNA splicing ISS GO:0008406 gonad development ISS GO:0008584 male gonad development IEP GO:0009888 tissue development ISS GO:0017148 negative regulation of translation IDA GO:0030308 negative regulation of cell growth IDA GO:0030325 adrenal gland development IGI GO:0030539 male genitalia development ISS GO:0030855 epithelial cell differentiation ISS GO:0032835 glomerulus development IGI GO:0032836 glomerular basement membrane development IMP GO:0035502 metanephric ureteric bud development ISS GO:0035802 adrenal cortex formation ISS GO:0043010 camera-type eye development ISS GO:0043066 negative regulation of apoptosis IGI GO:0045892 negative regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0045893 positive regulation of transcription, DNA-dependent IGI GO:0045944 positive regulation of transcription from RNA polymerase II promoter IEA GO:0045944 positive regulation of transcription from RNA polymerase II promoter ISS GO:0060231 mesenchymal to epithelial transition ISS GO:0060421 positive regulation of heart growth ISS GO:0060539 diaphragm development ISS GO:0060923 cardiac muscle cell fate commitment ISS GO:0061032 visceral serous pericardium development IGI GO:0071320 cellular response to cAMP IEP GO:0071371 cellular response to gonadotropin stimulus IDA GO:0072075 metanephric mesenchyme development ISS GO:0072112 glomerular visceral epithelial cell differentiation ISS GO:0072166 posterior mesonephric tubule development ISS GO:0072207 metanephric epithelium development IEP GO:0072284 metanephric S-shaped body morphogenesis IGI GO:0072302 negative regulation of metanephric glomerular mesangial cell proliferation ISS GO:2000020 positive regulation of male gonad development ISS GO:2000195 negative regulation of female gonad development ISS cellular_component GO:0005622 intracellular IEA GO:0005634 nucleus IDA GO:0005634 nucleus IEA GO:0005654 nucleoplasm IDA GO:0005654 nucleoplasm IEA GO:0005730 nucleolus IEA GO:0005737 cytoplasm ISS GO:0016607 nuclear speck IDA molecular_function GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription ISS GO:0003676 nucleic acid binding IEA GO:0003700 sequence-specific DNA binding transcription factor activity IEA GO:0003700 sequence-specific DNA binding transcription factor activity ISS GO:0003700 sequence-specific DNA binding transcription factor activity NAS GO:0003723 RNA binding IEA GO:0005515 protein binding IPI GO:0008270 zinc ion binding IDA GO:0008270 zinc ion binding IEA GO:0043565 sequence-specific DNA binding IDA GO:0043565 sequence-specific DNA binding IEA GO:0044212 transcription regulatory region DNA binding IDA GO:0046872 metal ion binding IEA GO:0070742 C2H2 zinc finger domain binding IPI

Protein-protein interaction details for WT1 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID WTAP Two-hybrid physical 11001926 WTAP Reconstituted Complex physical 11001926 WTAP Affinity Capture-Western physical 11001926 UBE2I Two-hybrid physical 8798754 UBE2I Reconstituted Complex physical 8798754 UBE2I Affinity Capture-Western physical 8798754 PAWR Two-hybrid physical 8943350 PAWR Reconstituted Complex physical 8943350 PAWR Reconstituted Complex physical 8943350 PAWR Affinity Capture-Western physical 8943350 TP53 Affinity Capture-Western physical 8389468 U2AF2 Two-hybrid physical 9784496 U2AF2 Affinity Capture-Western physical 9784496 U2AF2 Reconstituted Complex physical 9784496 MEN1 Affinity Capture-Western physical 21378168 MEN1 Affinity Capture-Western physical 21378168 SUZ12 Affinity Capture-Western physical 21378168 EZH2 Affinity Capture-Western physical 21378168 DNMT1 Affinity Capture-Western physical 21378168 EZH2 Affinity Capture-Western physical 21378168 SUZ12 Affinity Capture-Western physical 21378168 DVL3 Two-hybrid physical 21900206 NPM3 Two-hybrid physical 21900206 ZNF205 Two-hybrid physical 21900206 TAOK1 Two-hybrid physical 21900206