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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for CARD11 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001819 positive regulation of cytokine production IMP GO:0007165 signal transduction IEA GO:0030890 positive regulation of B cell proliferation IEA GO:0031295 T cell costimulation IDA GO:0042102 positive regulation of T cell proliferation IEA GO:0042981 regulation of apoptosis IEA GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade IEA GO:0045061 thymic T cell selection IEA GO:0045086 positive regulation of interleukin-2 biosynthetic process IEA GO:0045577 regulation of B cell differentiation IEA GO:0045580 regulation of T cell differentiation IEA GO:0050776 regulation of immune response IEA GO:0050852 T cell receptor signaling pathway TAS GO:0051092 positive regulation of NF-kappaB transcription factor activity IMP cellular_component GO:0005622 intracellular IEA GO:0005737 cytoplasm IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA GO:0005886 plasma membrane IEA GO:0042101 T cell receptor complex IDA GO:0045121 membrane raft IDA molecular_function GO:0004385 guanylate kinase activity NAS GO:0005515 protein binding IPI GO:0050700 CARD domain binding IPI

Protein-protein interaction details for CARD11 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID BCL10 Two-hybrid physical 11278692 BCL10 Affinity Capture-Western physical 11278692 BCL10 Reconstituted Complex physical 11278692 PDPK1 Affinity Capture-Western physical 15802604 PDPK1 Affinity Capture-Western physical 15802604 UBC Affinity Capture-Western physical 20008554 CBLB Affinity Capture-Western physical 19815501 CBLB Affinity Capture-Western physical 19815501 UBC Affinity Capture-Western physical 19815501 BCL10 Affinity Capture-Western physical 19815501 COPS5 Affinity Capture-Western physical 19444310 GPS1 Affinity Capture-Western physical 19444310 BCL10 Affinity Capture-Western physical 19444310 COPS5 Affinity Capture-Western physical 19444310 PRKCQ Affinity Capture-Western physical 20164171 MAP3K7 Affinity Capture-Western physical 20164171 FYB Affinity Capture-Western physical 20164171 PDPK1 Two-hybrid physical 21900206 TAB1 Two-hybrid physical 21900206 BCL10 Affinity Capture-Western physical 21513986