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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for TNFRSF11A (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001503 ossification IEA GO:0002250 adaptive immune response IMP GO:0002548 monocyte chemotaxis NAS GO:0007165 signal transduction TAS GO:0007267 cell-cell signaling TAS GO:0007275 multicellular organismal development IEA GO:0008284 positive regulation of cell proliferation TAS GO:0030316 osteoclast differentiation IMP GO:0032496 response to lipopolysaccharide ISS GO:0033209 tumor necrosis factor-mediated signaling pathway ISS GO:0034097 response to cytokine stimulus IMP GO:0034612 response to tumor necrosis factor ISS GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade RCA GO:0043507 positive regulation of JUN kinase activity IMP GO:0048535 lymph node development IEA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity IDA GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity ISS GO:0051092 positive regulation of NF-kappaB transcription factor activity IDA GO:0051092 positive regulation of NF-kappaB transcription factor activity IMP GO:0060086 circadian temperature homeostasis ISS GO:0060749 mammary gland alveolus development IEA GO:0070555 response to interleukin-1 ISS GO:0071812 positive regulation of fever generation by positive regulation of prostaglandin secretion ISS GO:0071847 TNFSF11-mediated signaling pathway IMP GO:0071848 positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling IMP cellular_component GO:0009897 external side of plasma membrane IDA GO:0016020 membrane IEA GO:0016021 integral to membrane IEA molecular_function GO:0004872 receptor activity IEA GO:0004888 transmembrane signaling receptor activity IDA GO:0005031 tumor necrosis factor receptor activity ISS GO:0005515 protein binding IPI GO:0019955 cytokine binding IPI GO:0046872 metal ion binding IEA

Protein-protein interaction details for TNFRSF11A (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID TAB2 Affinity Capture-Western physical 11809792 TRAF6 Affinity Capture-Western physical 11809792 MAP3K7 Affinity Capture-Western physical 11809792 TRAF5 Reconstituted Complex physical 9685412 TRAF6 Reconstituted Complex physical 9685412 TRAF2 Reconstituted Complex physical 9685412 TRAF2 Affinity Capture-Western physical 9685412 TRAF6 Reconstituted Complex physical 10075662 TRAF5 Reconstituted Complex physical 10075662 TRAF2 Reconstituted Complex physical 10075662 TRAF1 Reconstituted Complex physical 9852070 TRAF3 Reconstituted Complex physical 9852070 TRAF5 Reconstituted Complex physical 9852070 TRAF6 Reconstituted Complex physical 9852070 TRAF2 Reconstituted Complex physical 9852070 TRAF1 Reconstituted Complex physical 10025951 TRAF3 Reconstituted Complex physical 10025951 TRAF6 Reconstituted Complex physical 10025951 TRAF2 Reconstituted Complex physical 10025951 TRAF1 Affinity Capture-Western physical 10025951 TRAF3 Affinity Capture-Western physical 10025951 TRAF6 Affinity Capture-Western physical 10025951 TRAF2 Affinity Capture-Western physical 10025951