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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for SOCS2 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0001558 regulation of cell growth NAS GO:0006916 anti-apoptosis TAS GO:0007259 JAK-STAT cascade TAS GO:0007568 aging IEA GO:0009966 regulation of signal transduction NAS GO:0009968 negative regulation of signal transduction IEA GO:0032355 response to estradiol stimulus IDA GO:0032870 cellular response to hormone stimulus IDA GO:0035556 intracellular signal transduction IEA GO:0043434 response to peptide hormone stimulus IEA GO:0046425 regulation of JAK-STAT cascade TAS GO:0060396 growth hormone receptor signaling pathway IDA cellular_component GO:0005737 cytoplasm NAS molecular_function GO:0005070 SH3/SH2 adaptor activity TAS GO:0005131 growth hormone receptor binding NAS GO:0005148 prolactin receptor binding NAS GO:0005159 insulin-like growth factor receptor binding IPI GO:0005515 protein binding IPI GO:0008269 JAK pathway signal transduction adaptor activity TAS

Protein-protein interaction details for SOCS2 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PTK2 Two-hybrid physical 16189514 EPOR Two-hybrid physical 11781573 EPOR Affinity Capture-Western physical 11781573 GHR Reconstituted Complex physical 10585430 IGF1R Two-hybrid physical 9727029 IGF1R Reconstituted Complex physical 9727029 IGF1R Affinity Capture-Western physical 9727029 PRLR Affinity Capture-Western physical 10455112 SOCS1 Affinity Capture-Western physical 17898043 EPOR PCA physical 16961462 EPOR Reconstituted Complex physical 16961462 EPOR PCA physical 15644415 TCEB2 Affinity Capture-Western physical 21980433 TCEB1 Affinity Capture-Western physical 21980433 CUL5 Affinity Capture-Western physical 21980433 RNF7 Affinity Capture-Western physical 21980433 GHR Biochemical Activity physical 21980433 PTK2B Two-hybrid physical 20543098 RYBP Two-hybrid physical 20543098 PTK2B Affinity Capture-Western physical 20543098 PTK2B Affinity Capture-Western physical 20543098