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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene Ontology information for ARHGEF11 (Homo sapiens) (Information is obtained from AmiGO)

ID Term Evidence biological_process GO:0000910 cytokinesis NAS GO:0001558 regulation of cell growth NAS GO:0006915 apoptosis TAS GO:0006928 cellular component movement NAS GO:0006941 striated muscle contraction NAS GO:0007186 G-protein coupled receptor protein signaling pathway IDA GO:0007186 G-protein coupled receptor protein signaling pathway TAS GO:0007264 small GTPase mediated signal transduction TAS GO:0007266 Rho protein signal transduction IDA GO:0007411 axon guidance TAS GO:0008624 induction of apoptosis by extracellular signals TAS GO:0030010 establishment of cell polarity NAS GO:0030036 actin cytoskeleton organization NAS GO:0035023 regulation of Rho protein signal transduction IEA GO:0045893 positive regulation of transcription, DNA-dependent IDA GO:0048011 nerve growth factor receptor signaling pathway TAS GO:0051056 regulation of small GTPase mediated signal transduction TAS cellular_component GO:0005622 intracellular IC GO:0005622 intracellular IEA GO:0005737 cytoplasm IDA GO:0005737 cytoplasm IEA GO:0005794 Golgi apparatus IDA GO:0005829 cytosol TAS GO:0005886 plasma membrane IDA molecular_function GO:0001664 G-protein-coupled receptor binding IDA GO:0004871 signal transducer activity IEA GO:0005085 guanyl-nucleotide exchange factor activity IEA GO:0005089 Rho guanyl-nucleotide exchange factor activity IEA GO:0005089 Rho guanyl-nucleotide exchange factor activity TAS GO:0005096 GTPase activator activity IEA GO:0005515 protein binding IPI

Protein-protein interaction details for ARHGEF11 (Homo sapiens) (Information is obtained from BioGRID)

Interacting human protein Experiment Type PubMed ID PLXNB3 Two-hybrid physical 12183458 PLXNB1 Two-hybrid physical 12183458 PLXNB2 Two-hybrid physical 12183458 PLXNB1 Affinity Capture-Western physical 12730235 PLXNB1 Affinity Capture-Western physical 12123608 PLXNB2 Two-hybrid physical 12123608 PLXNB1 Affinity Capture-Western physical 12123608 PLXNB2 Affinity Capture-Western physical 12123608 PLXNB3 Affinity Capture-Western physical 12123608 PLXNB1 Co-localization physical 12123608 PLXNB2 Affinity Capture-Western physical 12183458 RHOA Biochemical Activity physical 10526156 RHOA Reconstituted Complex physical 10526156 PLXNB1 Affinity Capture-Western physical 12220504 PLXNB1 Affinity Capture-Western physical 12220504 PLXNB1 Two-hybrid physical 12220504 GNA13 Affinity Capture-Western physical 10026210 GNA12 Affinity Capture-Western physical 10026210 CDC42 Two-hybrid physical 20936779