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Species Homo sapiens Tissue uterus;;Endometrium;;Secretory (Luteal);;Mid (Receptive) Condition Normal
VS
Species Homo sapiens Tissue uterus;;Endometrium;;Secretory (Luteal);;Mid (Receptive) Condition Chemical treatment;;GnRH antagonist
Top 10            Top 100            All genes            References
Up-regulated Genes Score GO annotation	Down-regulated Genes Score GO annotation STAR 4 BP    MF    CC biological_process C21-steroid hormone biosynthetic process cellular lipid metabolic process glucocorticoid metabolic process lipid transport more... regulation of steroid biosynthetic process steroid biosynthetic process steroid metabolic process transport less... cellular_component mitochondrial intermembrane space mitochondrion molecular_function cholesterol binding cholesterol transporter activity lipid binding CXCL13 4 BP    MF    CC biological_process B cell chemotaxis activation of Rap GTPase activity cell-cell signaling chemotaxis more... chronic inflammatory response defense response to bacterium elevation of cytosolic calcium ion concentration endothelial cell chemotaxis to fibroblast growth factor germinal center formation immune response lymph node development lymphocyte chemotaxis across high endothelial venule negative regulation of apoptosis positive regulation of T cell chemotaxis positive regulation of cell-cell adhesion mediated by integrin positive regulation of integrin activation regulation of angiogenesis regulation of humoral immune response signal transduction less... cellular_component extracellular region extracellular space soluble fraction molecular_function CCR10 chemokine receptor binding CXCR3 chemokine receptor binding CXCR5 chemokine receptor binding chemokine activity more... fibroblast growth factor 2 binding heparin binding protein heterodimerization activity receptor agonist activity less... DKK1 4 BP    MF    CC biological_process cell morphogenesis involved in differentiation endoderm formation face morphogenesis forebrain development more... hair follicle development mesoderm formation multicellular organismal development negative regulation of BMP signaling pathway negative regulation of canonical Wnt receptor signaling pathway negative regulation of peptidyl-serine phosphorylation negative regulation of protein complex assembly negative regulation of skeletal muscle tissue development negative regulation of transcription from RNA polymerase II promoter positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway regulation of receptor internalization response to retinoic acid signal transduction less... cellular_component extracellular region extracellular space plasma membrane molecular_function growth factor activity low-density lipoprotein particle receptor binding protein binding receptor antagonist activity more... signal transducer activity less... TIMP3 4 BP    MF    CC biological_process aging central nervous system development negative regulation of membrane protein ectodomain proteolysis negative regulation of proteolysis more... response to amino acid stimulus response to estrogen stimulus response to folic acid response to hormone stimulus response to mechanical stimulus response to organic cyclic compound response to stimulus tissue regeneration visual perception less... cellular_component basement membrane cytoplasm extracellular matrix extracellular region more... molecular_function enzyme inhibitor activity metal ion binding metalloendopeptidase inhibitor activity protein binding more... IGFBP6 2 BP    MF    CC biological_process negative regulation of cell proliferation regulation of cell growth signal transduction cellular_component Golgi apparatus cytoplasm extracellular region extracellular space more... molecular_function insulin-like growth factor I binding insulin-like growth factor binding PAPSS2 2 BP    MF    CC biological_process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate metabolic process skeletal system development sulfate assimilation more... xenobiotic metabolic process less... cellular_component cytosol molecular_function ATP binding adenylylsulfate kinase activity kinase activity nucleotide binding more... nucleotidyltransferase activity sulfate adenylyltransferase (ATP) activity less... IL15 2 BP    MF    CC biological_process NK T cell proliferation aging cell-cell signaling cellular response to vitamin D more... extrathymic T cell selection hyaluronan metabolic process immune response lymph node development negative regulation of smooth muscle cell proliferation positive regulation of T cell proliferation positive regulation of cell proliferation positive regulation of immune response positive regulation of inflammatory response positive regulation of interleukin-17 production positive regulation of natural killer cell differentiation positive regulation of natural killer cell proliferation positive regulation of tissue remodeling positive regulation of tyrosine phosphorylation of Stat3 protein regulation of T cell differentiation regulation of defense response to virus by host response to nutrient levels signal transduction skeletal muscle atrophy less... cellular_component Golgi apparatus cytoplasm endosome extracellular region more... extracellular space integral to plasma membrane membrane fraction nucleus less... molecular_function cytokine activity cytokine receptor binding protein binding signal transducer activity more... COX7A1 2 BP    MF    CC biological_process generation of precursor metabolites and energy cellular_component integral to membrane membrane mitochondrial respiratory chain mitochondrion more... molecular_function cytochrome-c oxidase activity electron carrier activity IFI35 2 BP    MF    CC biological_process cytokine-mediated signaling pathway immune response response to virus type I interferon-mediated signaling pathway more... cellular_component cytosol nucleus molecular_function protein binding ID4 2 BP    MF    CC biological_process G1/S transition of mitotic cell cycle brain development cellular protein localization central nervous system myelination more... cerebral cortex neuron differentiation hippocampus development negative regulation of astrocyte differentiation negative regulation of fat cell differentiation negative regulation of neuron differentiation negative regulation of oligodendrocyte differentiation negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription, DNA-dependent neuroblast proliferation positive regulation of cell proliferation positive regulation of osteoblast differentiation regulation of transcription from RNA polymerase II promoter less... cellular_component cytoplasm nucleus molecular_function RNA polymerase II transcription factor binding protein binding transcription corepressor activity
Up-regulated Genes Score GO annotation	Down-regulated Genes Score GO annotation STAR 4 BP    MF    CC biological_process C21-steroid hormone biosynthetic process cellular lipid metabolic process glucocorticoid metabolic process lipid transport more... regulation of steroid biosynthetic process steroid biosynthetic process steroid metabolic process transport less... cellular_component mitochondrial intermembrane space mitochondrion molecular_function cholesterol binding cholesterol transporter activity lipid binding CXCL13 4 BP    MF    CC biological_process B cell chemotaxis activation of Rap GTPase activity cell-cell signaling chemotaxis more... chronic inflammatory response defense response to bacterium elevation of cytosolic calcium ion concentration endothelial cell chemotaxis to fibroblast growth factor germinal center formation immune response lymph node development lymphocyte chemotaxis across high endothelial venule negative regulation of apoptosis positive regulation of T cell chemotaxis positive regulation of cell-cell adhesion mediated by integrin positive regulation of integrin activation regulation of angiogenesis regulation of humoral immune response signal transduction less... cellular_component extracellular region extracellular space soluble fraction molecular_function CCR10 chemokine receptor binding CXCR3 chemokine receptor binding CXCR5 chemokine receptor binding chemokine activity more... fibroblast growth factor 2 binding heparin binding protein heterodimerization activity receptor agonist activity less... DKK1 4 BP    MF    CC biological_process cell morphogenesis involved in differentiation endoderm formation face morphogenesis forebrain development more... hair follicle development mesoderm formation multicellular organismal development negative regulation of BMP signaling pathway negative regulation of canonical Wnt receptor signaling pathway negative regulation of peptidyl-serine phosphorylation negative regulation of protein complex assembly negative regulation of skeletal muscle tissue development negative regulation of transcription from RNA polymerase II promoter positive regulation of heart induction by negative regulation of canonical Wnt receptor signaling pathway regulation of receptor internalization response to retinoic acid signal transduction less... cellular_component extracellular region extracellular space plasma membrane molecular_function growth factor activity low-density lipoprotein particle receptor binding protein binding receptor antagonist activity more... signal transducer activity less... TIMP3 4 BP    MF    CC biological_process aging central nervous system development negative regulation of membrane protein ectodomain proteolysis negative regulation of proteolysis more... response to amino acid stimulus response to estrogen stimulus response to folic acid response to hormone stimulus response to mechanical stimulus response to organic cyclic compound response to stimulus tissue regeneration visual perception less... cellular_component basement membrane cytoplasm extracellular matrix extracellular region more... molecular_function enzyme inhibitor activity metal ion binding metalloendopeptidase inhibitor activity protein binding more... IGFBP6 2 BP    MF    CC biological_process negative regulation of cell proliferation regulation of cell growth signal transduction cellular_component Golgi apparatus cytoplasm extracellular region extracellular space more... molecular_function insulin-like growth factor I binding insulin-like growth factor binding PAPSS2 2 BP    MF    CC biological_process 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process 3'-phosphoadenosine 5'-phosphosulfate metabolic process skeletal system development sulfate assimilation more... xenobiotic metabolic process less... cellular_component cytosol molecular_function ATP binding adenylylsulfate kinase activity kinase activity nucleotide binding more... nucleotidyltransferase activity sulfate adenylyltransferase (ATP) activity less... IL15 2 BP    MF    CC biological_process NK T cell proliferation aging cell-cell signaling cellular response to vitamin D more... extrathymic T cell selection hyaluronan metabolic process immune response lymph node development negative regulation of smooth muscle cell proliferation positive regulation of T cell proliferation positive regulation of cell proliferation positive regulation of immune response positive regulation of inflammatory response positive regulation of interleukin-17 production positive regulation of natural killer cell differentiation positive regulation of natural killer cell proliferation positive regulation of tissue remodeling positive regulation of tyrosine phosphorylation of Stat3 protein regulation of T cell differentiation regulation of defense response to virus by host response to nutrient levels signal transduction skeletal muscle atrophy less... cellular_component Golgi apparatus cytoplasm endosome extracellular region more... extracellular space integral to plasma membrane membrane fraction nucleus less... molecular_function cytokine activity cytokine receptor binding protein binding signal transducer activity more... COX7A1 2 BP    MF    CC biological_process generation of precursor metabolites and energy cellular_component integral to membrane membrane mitochondrial respiratory chain mitochondrion more... molecular_function cytochrome-c oxidase activity electron carrier activity IFI35 2 BP    MF    CC biological_process cytokine-mediated signaling pathway immune response response to virus type I interferon-mediated signaling pathway more... cellular_component cytosol nucleus molecular_function protein binding ID4 2 BP    MF    CC biological_process G1/S transition of mitotic cell cycle brain development cellular protein localization central nervous system myelination more... cerebral cortex neuron differentiation hippocampus development negative regulation of astrocyte differentiation negative regulation of fat cell differentiation negative regulation of neuron differentiation negative regulation of oligodendrocyte differentiation negative regulation of transcription from RNA polymerase II promoter negative regulation of transcription, DNA-dependent neuroblast proliferation positive regulation of cell proliferation positive regulation of osteoblast differentiation regulation of transcription from RNA polymerase II promoter less... cellular_component cytoplasm nucleus molecular_function RNA polymerase II transcription factor binding protein binding transcription corepressor activity TGFBR2 2 BP    MF    CC biological_process activation of protein kinase activity apoptosis blood vessel development brain development more... embryonic cranial skeleton morphogenesis embryonic hemopoiesis heart development myeloid dendritic cell differentiation palate development pathway-restricted SMAD protein phosphorylation patterning of blood vessels peptidyl-serine phosphorylation peptidyl-threonine phosphorylation positive regulation of B cell tolerance induction positive regulation of NK T cell differentiation positive regulation of T cell tolerance induction positive regulation of cell proliferation positive regulation of mesenchymal cell proliferation positive regulation of reactive oxygen species metabolic process positive regulation of tolerance induction to self antigen protein phosphorylation regulation of cell proliferation regulation of growth response to cholesterol response to drug transforming growth factor beta receptor signaling pathway vasculogenesis less... cellular_component caveola external side of plasma membrane integral to membrane membrane more... plasma membrane receptor complex transforming growth factor beta receptor complex less... molecular_function ATP binding SMAD binding glycosaminoglycan binding metal ion binding more... nucleotide binding protein binding protein serine/threonine kinase activity receptor activity receptor signaling protein serine/threonine kinase activity transferase activity, transferring phosphorus-containing groups transforming growth factor beta binding transforming growth factor beta receptor activity, type II transforming growth factor beta-activated receptor activity transmembrane receptor protein serine/threonine kinase activity type I transforming growth factor beta receptor binding type III transforming growth factor beta receptor binding less... CYP4B1 2 BP    MF    CC biological_process biphenyl metabolic process cellular aromatic compound metabolic process exogenous drug catabolic process fluorene metabolic process more... oxidation-reduction process xenobiotic metabolic process less... cellular_component endoplasmic reticulum endoplasmic reticulum membrane membrane microsome more... molecular_function aromatase activity drug binding electron carrier activity fluorene oxygenase activity more... heme binding metal ion binding monooxygenase activity oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen oxygen binding less... HOXC6 2 BP    MF    CC biological_process multicellular organismal development regulation of transcription from RNA polymerase II promoter cellular_component nucleus molecular_function DNA binding sequence-specific DNA binding sequence-specific DNA binding transcription factor activity transcription corepressor activity more... IFITM1 2 BP    MF    CC biological_process cell surface receptor linked signaling pathway cytokine-mediated signaling pathway innate immune response negative regulation of cell proliferation more... regulation of immune response response to biotic stimulus response to virus type I interferon-mediated signaling pathway less... cellular_component integral to membrane plasma membrane molecular_function receptor signaling protein activity EMP1 2 BP    MF    CC biological_process cell growth cell proliferation epidermis development multicellular organismal development more... cellular_component integral to membrane membrane membrane fraction plasma membrane more... molecular_function IER3 2 BP    MF    CC biological_process anatomical structure morphogenesis anti-apoptosis apoptosis cellular_component integral to membrane membrane molecular_function protein binding TIMP1 2 BP    MF    CC biological_process aging blood coagulation cell activation erythrocyte maturation more... negative regulation of apoptosis negative regulation of membrane protein ectodomain proteolysis platelet activation platelet degranulation positive regulation of cell proliferation response to cytokine stimulus response to peptide hormone stimulus wound healing less... cellular_component basement membrane extracellular region platelet alpha granule lumen molecular_function enzyme inhibitor activity metal ion binding metalloendopeptidase inhibitor activity protein binding more... CCL8 2 BP    MF    CC biological_process calcium ion transport cell-cell signaling chemotaxis exocytosis more... immune response inflammatory response response to virus signal transduction less... cellular_component extracellular region extracellular space molecular_function chemokine activity heparin binding signal transducer activity ALDH1A3 2 BP    MF    CC biological_process embryonic camera-type eye development embryonic eye morphogenesis face development kidney development more... nucleus accumbens development olfactory pit development optic cup morphogenesis involved in camera-type eye development pituitary gland development positive regulation of apoptosis response to drug retinal metabolic process retinoic acid biosynthetic process retinoic acid metabolic process less... cellular_component cytoplasm molecular_function NAD+ binding aldehyde dehydrogenase (NAD) activity aldehyde dehydrogenase [NAD(P)+] activity oxidoreductase activity more... oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor protein homodimerization activity thyroid hormone binding less... APOE 2 BP    MF    CC biological_process Cdc42 protein signal transduction G-protein coupled receptor protein signaling pathway aging anti-apoptosis more... artery morphogenesis cGMP-mediated signaling cardiovascular system development cell death cellular calcium ion homeostasis cellular response to growth factor stimulus cholesterol catabolic process cholesterol efflux cholesterol homeostasis cholesterol metabolic process chylomicron remnant clearance cytoskeleton organization high-density lipoprotein particle assembly high-density lipoprotein particle clearance high-density lipoprotein particle remodeling induction of apoptosis intracellular transport lipid homeostasis lipid metabolic process lipoprotein biosynthetic process lipoprotein catabolic process lipoprotein metabolic process low-density lipoprotein particle remodeling maintenance of location in cell negative regulation of MAP kinase activity negative regulation of blood coagulation negative regulation of blood vessel endothelial cell migration negative regulation of cholesterol biosynthetic process negative regulation of endothelial cell proliferation negative regulation of inflammatory response negative regulation of platelet activation nitric oxide mediated signal transduction peripheral nervous system axon regeneration phospholipid efflux positive regulation of cGMP biosynthetic process positive regulation of cholesterol efflux positive regulation of cholesterol esterification positive regulation of low-density lipoprotein particle receptor catabolic process positive regulation of membrane protein ectodomain proteolysis positive regulation of nitric-oxide synthase activity receptor-mediated endocytosis regulation of axon extension regulation of gene expression regulation of neuronal synaptic plasticity response to dietary excess response to ethanol response to oxidative stress response to reactive oxygen species reverse cholesterol transport synaptic transmission, cholinergic triglyceride metabolic process vasodilation very-low-density lipoprotein particle clearance very-low-density lipoprotein particle remodeling less... cellular_component Golgi apparatus chylomicron cytoplasm dendrite more... early endosome extracellular region extracellular space extrinsic to external side of plasma membrane high-density lipoprotein particle intermediate-density lipoprotein particle late endosome low-density lipoprotein particle microtubule neuronal cell body plasma membrane very-low-density lipoprotein particle less... molecular_function antioxidant activity beta-amyloid binding cholesterol transporter activity heparin binding more... identical protein binding lipid binding lipid transporter activity lipoprotein particle binding low-density lipoprotein particle receptor binding metal chelating activity phosphatidylcholine-sterol O-acyltransferase activator activity phospholipid binding protein binding protein heterodimerization activity protein homodimerization activity tau protein binding very-low-density lipoprotein particle receptor binding less... BCL3 2 BP    MF    CC biological_process DNA damage response, signal transduction by p53 class mediator DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis I-kappaB kinase/NF-kappaB cascade T-helper 1 type immune response more... T-helper 2 cell differentiation antimicrobial humoral response defense response to bacterium defense response to protozoan extracellular matrix organization follicular dendritic cell differentiation germinal center formation humoral immune response mediated by circulating immunoglobulin maintenance of protein location in nucleus marginal zone B cell differentiation negative regulation of apoptosis negative regulation of interleukin-8 biosynthetic process negative regulation of transcription, DNA-dependent negative regulation of tumor necrosis factor biosynthetic process positive regulation of interferon-gamma production positive regulation of interleukin-10 biosynthetic process positive regulation of transcription from RNA polymerase II promoter positive regulation of transcription, DNA-dependent positive regulation of translation protein import into nucleus, translocation regulation of DNA binding regulation of NF-kappaB import into nucleus regulation of apoptosis response to DNA damage stimulus response to UV-C response to virus spleen development transcription, DNA-dependent less... cellular_component Bcl3-Bcl10 complex Bcl3/NF-kappaB2 complex cytoplasm nucleus more... perinuclear region of cytoplasm protein complex less... molecular_function protein binding protein binding, bridging sequence-specific DNA binding transcription factor activity transcription factor binding more... S100A6 2 BP    MF    CC biological_process axonogenesis positive regulation of fibroblast proliferation signal transduction cellular_component cytoplasm cytosol extrinsic to internal side of plasma membrane nuclear envelope more... nucleus perinuclear region of cytoplasm plasma membrane ruffle less... molecular_function S100 beta binding calcium ion binding calcium-dependent protein binding ion transmembrane transporter activity more... protein binding protein homodimerization activity tropomyosin binding less... CTSW 2 BP    MF    CC biological_process immune response proteolysis cellular_component molecular_function cysteine-type endopeptidase activity cysteine-type peptidase activity peptidase activity IFITM3 2 BP    MF    CC biological_process cytokine-mediated signaling pathway immune response innate immune response response to biotic stimulus more... response to virus type I interferon-mediated signaling pathway less... cellular_component integral to membrane membrane plasma membrane molecular_function ANXA4 2 BP    MF    CC biological_process anti-apoptosis negative regulation of coagulation signal transduction cellular_component cytoplasm molecular_function calcium ion binding calcium-dependent phospholipid binding phospholipase inhibitor activity S100A4 2 BP    MF    CC biological_process epithelial to mesenchymal transition positive regulation of I-kappaB kinase/NF-kappaB cascade cellular_component neuron projection nucleus perinuclear region of cytoplasm molecular_function RAGE receptor binding calcium ion binding calcium-dependent protein binding identical protein binding more... protein binding less... ANGPTL1 2 BP    MF    CC biological_process signal transduction transmembrane receptor protein tyrosine kinase signaling pathway cellular_component extracellular region extracellular space molecular_function receptor binding SLC16A7 2 BP    MF    CC biological_process organic anion transport pyruvate transport transmembrane transport cellular_component integral to membrane integral to plasma membrane membrane fraction plasma membrane more... molecular_function pyruvate secondary active transmembrane transporter activity secondary active monocarboxylate transmembrane transporter activity symporter activity CD14 2 BP    MF    CC biological_process Toll signaling pathway apoptosis cell surface receptor linked signaling pathway cellular response to lipopolysaccharide more... cellular response to lipoteichoic acid inflammatory response innate immune response phagocytosis positive regulation of cytokine secretion positive regulation of tumor necrosis factor production response to heat response to lipopolysaccharide less... cellular_component anchored to membrane cell surface extracellular region extracellular space more... membrane raft plasma membrane less... molecular_function lipopolysaccharide binding lipoteichoic acid binding opsonin receptor activity peptidoglycan receptor activity more... CADM1 2 BP    MF    CC biological_process T cell mediated cytotoxicity activated T cell proliferation adherens junction organization apoptosis more... brain development calcium-independent cell-cell adhesion cell adhesion cell differentiation cell junction assembly cell recognition cell-cell junction organization detection of stimulus heterophilic cell-cell adhesion homophilic cell adhesion liver development multicellular organismal development positive regulation of cytokine secretion positive regulation of natural killer cell mediated cytotoxicity spermatogenesis susceptibility to natural killer cell mediated cytotoxicity synapse assembly unidimensional cell growth less... cellular_component axon basolateral plasma membrane cell-cell junction dendrite more... integral to membrane membrane plasma membrane synapse synaptic vesicle synaptosome less... molecular_function PDZ domain binding cell adhesion molecule binding protein C-terminus binding protein homodimerization activity more... receptor binding less... ISG15 2 BP    MF    CC biological_process ISG15-protein conjugation cell-cell signaling cytokine-mediated signaling pathway innate immune response more... interspecies interaction between organisms modification-dependent protein catabolic process negative regulation of type I interferon production response to virus type I interferon-mediated signaling pathway less... cellular_component cytoplasm cytosol extracellular region extracellular space more... molecular_function protein tag THY1 2 BP    MF    CC biological_process T cell receptor signaling pathway angiogenesis cell-cell adhesion cytoskeleton organization more... focal adhesion assembly negative regulation of T cell receptor signaling pathway negative regulation of axonogenesis negative regulation of cell migration negative regulation of protein kinase activity positive regulation of GTPase activity positive regulation of Rho GTPase activity positive regulation of T cell activation positive regulation of release of sequestered calcium ion into cytosol retinal cone cell development less... cellular_component anchored to external side of plasma membrane cytosol dendrite endoplasmic reticulum more... external side of plasma membrane growth cone integral to plasma membrane membrane raft plasma membrane less... molecular_function GPI anchor binding Rho GTPase activator activity enzyme binding integrin binding more... protein binding protein kinase binding less... VCAN 2 BP    MF    CC biological_process axon regeneration cell adhesion cell recognition glial cell migration more... heart development multicellular organismal development response to wounding less... cellular_component extracellular matrix extracellular region extracellular space proteinaceous extracellular matrix more... molecular_function binding calcium ion binding glycosaminoglycan binding hyaluronic acid binding more... sugar binding less... PTGDS 2 BP    MF    CC biological_process fatty acid biosynthetic process lipid metabolic process prostaglandin biosynthetic process regulation of circadian sleep/wake cycle, sleep more... response to glucocorticoid stimulus transport less... cellular_component Golgi apparatus cytoplasm extracellular region extracellular space more... membrane nuclear membrane nucleus perinuclear region of cytoplasm rough endoplasmic reticulum less... molecular_function binding fatty acid binding isomerase activity prostaglandin-D synthase activity more... retinoid binding transporter activity less... IGFBP5 2 BP    MF    CC biological_process cellular response to cAMP cellular response to organic cyclic compound glucose homeostasis glucose metabolic process more... hair follicle morphogenesis intracellular signal transduction mammary gland involution negative regulation of cell migration negative regulation of insulin-like growth factor receptor signaling pathway negative regulation of smooth muscle cell migration negative regulation of smooth muscle cell proliferation negative regulation of translation osteoblast differentiation positive regulation of protein kinase B signaling cascade regulation of cell growth signal transduction skeletal muscle tissue growth striated muscle cell differentiation less... cellular_component extracellular region insulin-like growth factor binding protein complex molecular_function fibronectin binding insulin-like growth factor I binding insulin-like growth factor binding protein binding more... SERPINA3 2 BP    MF    CC biological_process acute-phase response inflammatory response maintenance of gastrointestinal epithelium negative regulation of endopeptidase activity more... regulation of lipid metabolic process regulation of proteolysis less... cellular_component extracellular region intracellular nucleus molecular_function DNA binding peptidase inhibitor activity protein binding serine-type endopeptidase inhibitor activity more... COL15A1 2 BP    MF    CC biological_process angiogenesis cell adhesion cell differentiation multicellular organismal development more... signal transduction less... cellular_component basement membrane collagen type XV extracellular matrix extracellular region more... extracellular space integral to membrane less... molecular_function binding extracellular matrix structural constituent structural molecule activity CEBPG 2 BP    MF    CC biological_process B cell differentiation enucleate erythrocyte differentiation immune response liver development more... mRNA metabolic process natural killer cell mediated cytotoxicity negative regulation of sequence-specific DNA binding transcription factor activity positive regulation of DNA binding positive regulation of DNA repair positive regulation of interferon-gamma biosynthetic process positive regulation of sequence-specific DNA binding transcription factor activity regulation of transcription from RNA polymerase II promoter less... cellular_component nucleolus nucleus molecular_function DNA binding double-stranded DNA binding protein binding protein heterodimerization activity more... sequence-specific DNA binding transcription factor binding less... IFITM2 2 BP    MF    CC biological_process cytokine-mediated signaling pathway immune response innate immune response response to biotic stimulus more... response to virus type I interferon-mediated signaling pathway less... cellular_component integral to membrane membrane plasma membrane molecular_function IGFBP4 2 BP    MF    CC biological_process DNA metabolic process cell proliferation inflammatory response regulation of cell growth more... signal transduction skeletal system development less... cellular_component extracellular region extracellular space molecular_function insulin-like growth factor binding IGF2 2 BP    MF    CC biological_process carbohydrate metabolic process exocrine pancreas development glucose metabolic process insulin receptor signaling pathway more... multicellular organismal development organ morphogenesis ossification osteoblast differentiation positive regulation of MAPKKK cascade positive regulation of activated T cell proliferation positive regulation of catalytic activity positive regulation of cell division positive regulation of cell proliferation positive regulation of glycogen (starch) synthase activity positive regulation of glycogen biosynthetic process positive regulation of insulin receptor signaling pathway positive regulation of mitosis positive regulation of peptidyl-tyrosine phosphorylation positive regulation of protein kinase B signaling cascade positive regulation of protein phosphorylation positive regulation of protein serine/threonine kinase activity positive regulation of receptor activity positive regulation of steroid hormone biosynthetic process positive regulation of transcription from RNA polymerase II promoter regulation of gene expression by genetic imprinting regulation of transcription, DNA-dependent response to drug response to estradiol stimulus response to nicotine response to nutrient levels response to radiation skeletal system development striated muscle cell differentiation less... cellular_component extracellular region extracellular space molecular_function growth factor activity hormone activity insulin receptor binding insulin-like growth factor receptor binding more... protein binding protein serine/threonine kinase activator activity receptor activator activity less...
Up-regulated Genes Score	Down-regulated Genes Score STAR 4 CXCL13 4 DKK1 4 TIMP3 4 IGFBP6 2 PAPSS2 2 IL15 2 COX7A1 2 IFI35 2 ID4 2 TGFBR2 2 CYP4B1 2 HOXC6 2 IFITM1 2 EMP1 2 IER3 2 TIMP1 2 CCL8 2 ALDH1A3 2 APOE 2 BCL3 2 S100A6 2 CTSW 2 IFITM3 2 ANXA4 2 S100A4 2 ANGPTL1 2 SLC16A7 2 CD14 2 CADM1 2 ISG15 2 THY1 2 VCAN 2 PTGDS 2 IGFBP5 2 SERPINA3 2 COL15A1 2 CEBPG 2 IFITM2 2 IGFBP4 2 IGF2 2
Identifiers Repository Data-sets 18497344 PubMed 3
Up-regulated(0) Down-regulated(41)