Expressed genes |
Gene |
Score |
GO annotation |
DDR2 |
14 |
BP MF CC |
biological_process | - cell adhesion
- chondrocyte proliferation
- ossification
- peptidyl-tyrosine phosphorylation
more... - positive regulation of cell cycle arrest
- positive regulation of cell proliferation
- positive regulation of fibroblast migration
- positive regulation of fibroblast proliferation
- positive regulation of osteoblast differentiation
- positive regulation of protein kinase activity
- positive regulation of sequence-specific DNA binding transcription factor activity
- protein autophosphorylation
- regulation of bone mineralization
- regulation of extracellular matrix disassembly
- signal transduction
- transmembrane receptor protein tyrosine kinase signaling pathway
less...
|
| cellular_component | - integral to plasma membrane
- plasma membrane
|
| | |
TAF9 |
10 |
BP MF CC |
biological_process | - gene expression
- histone H3 acetylation
- negative regulation of apoptosis
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process
more... - positive regulation of cell growth
- positive regulation of response to cytokine stimulus
- positive regulation of transcription from RNA polymerase II promoter
- regulation of transcription, DNA-dependent
- response to DNA damage stimulus
- response to interleukin-1
- transcription elongation from RNA polymerase II promoter
- transcription from RNA polymerase II promoter
- transcription initiation from RNA polymerase II promoter
- transcription initiation, DNA-dependent
- viral reproduction
less...
|
| cellular_component | - Cajal body
- MLL1 complex
- PCAF complex
- STAGA complex
more... - nucleolus
- nucleoplasm
- nucleus
- pre-snoRNP complex
- transcription factor TFIID complex
- transcription factor TFTC complex
less...
|
| molecular_function | - ATP binding
- C2H2 zinc finger domain binding
- DNA binding
- activating transcription factor binding
more... - adenylate kinase activity
- histone acetyltransferase activity
- kinase activity
- nucleotide binding
- p53 binding
- protein binding
- transcription coactivator activity
- transcription regulatory region DNA binding
- transferase activity
less...
|
| |
WFDC2 |
10 |
BP MF CC |
biological_process | - negative regulation of endopeptidase activity
- proteolysis
- spermatogenesis
|
| cellular_component | - extracellular region
- extracellular space
|
| molecular_function | - endopeptidase inhibitor activity
- peptidase inhibitor activity
- serine-type endopeptidase inhibitor activity
|
| |
PRKAR2B |
10 |
BP MF CC |
biological_process | - G2/M transition of mitotic cell cycle
- activation of phospholipase C activity
- activation of protein kinase A activity
- blood coagulation
more... - cellular response to glucagon stimulus
- energy reserve metabolic process
- fatty acid metabolic process
- intracellular signal transduction
- learning
- mitotic cell cycle
- nerve growth factor receptor signaling pathway
- regulation of insulin secretion
- regulation of protein kinase activity
- regulation of protein phosphorylation
- signal transduction
- transmembrane transport
- water transport
less...
|
| cellular_component | - cAMP-dependent protein kinase complex
- centrosome
- cytoplasm
- cytosol
more... - membrane fraction
- membrane raft
- mitochondrial inner membrane
- perinuclear region of cytoplasm
- plasma membrane
- soluble fraction
less...
|
| | |
CCNA1 |
10 |
BP MF CC |
biological_process | - G1/S transition of mitotic cell cycle
- G2/M transition of mitotic cell cycle
- cell division
- male meiosis I
more... - mitosis
- mitotic cell cycle
- regulation of cyclin-dependent protein kinase activity
- regulation of transcription involved in G1/S phase of mitotic cell cycle
- spermatogenesis
less...
|
| cellular_component | - cytosol
- microtubule cytoskeleton
- nucleoplasm
- nucleus
more...
|
| molecular_function | - protein binding
- protein kinase binding
|
| |
ID2 |
10 |
BP MF CC |
biological_process | - Peyer's patch development
- adipose tissue development
- bundle of His development
- cell maturation
more... - cellular response to lithium ion
- cellular senescence
- embryonic digestive tract morphogenesis
- endodermal digestive tract morphogenesis
- entrainment of circadian clock
- epithelial cell differentiation involved in mammary gland alveolus development
- leukocyte differentiation
- mammary gland alveolus development
- mammary gland epithelial cell proliferation
- metanephros development
- multicellular organismal development
- natural killer cell differentiation
- negative regulation of B cell differentiation
- negative regulation of DNA binding
- negative regulation of gene expression
- negative regulation of neural precursor cell proliferation
- negative regulation of neuron differentiation
- negative regulation of oligodendrocyte differentiation
- negative regulation of osteoblast differentiation
- negative regulation of sequence-specific DNA binding transcription factor activity
- negative regulation of transcription from RNA polymerase II promoter
- negative regulation of transcription, DNA-dependent
- neuron fate commitment
- olfactory bulb development
- oligodendrocyte development
- positive regulation of astrocyte differentiation
- positive regulation of blood pressure
- positive regulation of cell cycle
- positive regulation of cell cycle arrest
- positive regulation of erythrocyte differentiation
- positive regulation of fat cell differentiation
- positive regulation of gene expression
- positive regulation of smooth muscle cell proliferation
- positive regulation of transcription, DNA-dependent
- regulation of lipid metabolic process
less...
|
| cellular_component | - chromatin
- cytoplasm
- cytosol
- nucleolus
more... - nucleus
- protein complex
less...
|
| | |
MSX1 |
10 |
BP MF CC |
biological_process | - apoptotic nuclear change
- cell morphogenesis
- embryonic nail plate morphogenesis
- face morphogenesis
more... - multicellular organismal development
- negative regulation of cell growth
- negative regulation of transcription from RNA polymerase II promoter
- odontogenesis of dentine-containing tooth
- positive regulation of DNA damage response, signal transduction by p53 class mediator
- positive regulation of apoptosis
- protein localization to nucleus
- protein stabilization
less...
|
| | molecular_function | - p53 binding
- sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
|
| |
MGST2 |
10 |
BP MF CC |
| | molecular_function | - enzyme activator activity
- glutathione peroxidase activity
- glutathione transferase activity
- leukotriene-C4 synthase activity
more... - transferase activity
less...
|
| |
MMP7 |
10 |
BP MF CC |
| cellular_component | - extracellular region
- extracellular space
- proteinaceous extracellular matrix
|
| molecular_function | - metal ion binding
- metalloendopeptidase activity
- peptidase activity
- zinc ion binding
more...
|
| |
PDGFRA |
10 |
BP MF CC |
biological_process | - Leydig cell differentiation
- adrenal gland development
- cardiac myofibril assembly
- cell activation
more... - cellular response to amino acid stimulus
- estrogen metabolic process
- extracellular matrix organization
- face morphogenesis
- female gonad development
- gliogenesis
- in utero embryonic development
- inner ear development
- lung development
- luteinization
- male genitalia development
- metanephric glomerular capillary formation
- odontogenesis of dentine-containing tooth
- palate development
- peptidyl-tyrosine phosphorylation
- platelet-derived growth factor receptor signaling pathway
- platelet-derived growth factor receptor-alpha signaling pathway
- positive regulation of DNA replication
- positive regulation of cell migration
- positive regulation of cell proliferation
- positive regulation of fibroblast proliferation
- protein autophosphorylation
- response to cytokine stimulus
- response to estradiol stimulus
- response to hormone stimulus
- response to hyperoxia
- response to inorganic substance
- retina vasculature development in camera-type eye
- signal transduction involved in regulation of gene expression
- skeletal system morphogenesis
- vascular endothelial growth factor receptor signaling pathway
- wound healing
less...
|
| cellular_component | - cytoplasm
- integral to plasma membrane
- membrane
- nucleus
more... - plasma membrane
less...
|
| molecular_function | - ATP binding
- growth factor binding
- nucleotide binding
- phosphatidylinositol 3-kinase binding
more... - platelet-derived growth factor alpha-receptor activity
- platelet-derived growth factor binding
- platelet-derived growth factor receptor binding
- protein homodimerization activity
- protein kinase activity
- protein tyrosine kinase activity
- receptor activity
- transferase activity, transferring phosphorus-containing groups
- vascular endothelial growth factor-activated receptor activity
less...
|
| |
GZMA |
10 |
BP MF CC |
biological_process | - apoptosis
- cleavage of lamin
- cytolysis
- immune response
more... - negative regulation of DNA binding
- negative regulation of endodeoxyribonuclease activity
- negative regulation of oxidoreductase activity
- positive regulation of apoptosis
- proteolysis involved in cellular protein catabolic process
less...
|
| cellular_component | - extracellular region
- immunological synapse
- nucleus
|
| molecular_function | - peptidase activity
- protein binding
- protein homodimerization activity
- serine-type endopeptidase activity
more...
|
| |
TIMP1 |
10 |
BP MF CC |
biological_process | - aging
- blood coagulation
- cell activation
- erythrocyte maturation
more... - negative regulation of apoptosis
- negative regulation of membrane protein ectodomain proteolysis
- platelet activation
- platelet degranulation
- positive regulation of cell proliferation
- response to cytokine stimulus
- response to peptide hormone stimulus
- wound healing
less...
|
| cellular_component | - basement membrane
- extracellular region
- platelet alpha granule lumen
|
| molecular_function | - enzyme inhibitor activity
- metal ion binding
- metalloendopeptidase inhibitor activity
- protein binding
more...
|
| |
LAPTM4A |
10 |
BP MF CC |
| cellular_component | - Golgi apparatus
- endomembrane system
- integral to membrane
- membrane
more...
|
| | |
TSC2 |
10 |
BP MF CC |
biological_process | - acute-phase response
- cell cycle arrest
- cell projection organization
- endocytosis
more... - establishment of protein localization
- fibroblast growth factor receptor signaling pathway
- heart development
- insulin receptor signaling pathway
- insulin-like growth factor receptor signaling pathway
- negative regulation of MAP kinase activity
- negative regulation of TOR signaling cascade
- negative regulation of Wnt receptor signaling pathway
- negative regulation of cell proliferation
- negative regulation of cell size
- negative regulation of epithelial cell proliferation
- negative regulation of phosphatidylinositol 3-kinase cascade
- negative regulation of protein kinase B signaling cascade
- negative regulation of protein kinase activity
- nerve growth factor receptor signaling pathway
- neural tube closure
- phosphatidylinositol-mediated signaling
- positive chemotaxis
- positive regulation of GTPase activity
- protein heterooligomerization
- protein homooligomerization
- protein import into nucleus
- protein kinase B signaling cascade
- protein localization
- regulation of cell cycle
- regulation of endocytosis
- regulation of insulin receptor signaling pathway
- regulation of small GTPase mediated signal transduction
- response to hypoxia
- signal transduction
- vesicle-mediated transport
less...
|
| cellular_component | - Golgi apparatus
- TSC1-TSC2 complex
- caveola
- cytoplasm
more... - cytoskeletal part
- cytosol
- dendrite
- growth cone
- intracellular
- membrane
- membrane fraction
- microsome
- neuronal cell body
- nucleus
- perinuclear region of cytoplasm
- protein complex
less...
|
| | |
MARCKSL1 |
10 |
BP MF CC |
biological_process | - positive regulation of cell proliferation
- vesicle-mediated transport
|
| | | |
PMP22 |
10 |
BP MF CC |
| cellular_component | - compact myelin
- integral to membrane
- membrane
- tight junction
more...
|
| | |
HOXB5 |
10 |
BP MF CC |
| | molecular_function | - sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
|
| |
CRABP2 |
10 |
BP MF CC |
biological_process | - embryonic forelimb morphogenesis
- epidermis development
- regulation of transcription, DNA-dependent
- retinoic acid metabolic process
more... - signal transduction
less...
|
| cellular_component | - cytoplasm
- nucleolus
- nucleus
|
| | |
RCHY1 |
10 |
BP MF CC |
| cellular_component | - cytoplasm
- nuclear speck
- nucleolus
- nucleus
more... - ubiquitin ligase complex
less...
|
| molecular_function | - electron carrier activity
- ligase activity
- metal ion binding
- p53 binding
more... - protein binding
- protein homodimerization activity
- receptor binding
- ubiquitin-protein ligase activity
- zinc ion binding
less...
|
| |
CKS2 |
10 |
BP MF CC |
biological_process | - cell cycle
- cell division
- cell proliferation
- meiosis I
more... - phosphatidylinositol-mediated signaling
- regulation of cyclin-dependent protein kinase activity
- spindle organization
less...
|
| | molecular_function | - cyclin-dependent protein kinase regulator activity
|
| |
MMP11 |
10 |
BP MF CC |
biological_process | - collagen catabolic process
- multicellular organismal development
- proteolysis
|
| cellular_component | - extracellular matrix
- extracellular region
- proteinaceous extracellular matrix
|
| molecular_function | - calcium ion binding
- metal ion binding
- metalloendopeptidase activity
- peptidase activity
more... - zinc ion binding
less...
|
| |
C6orf108 |
10 |
BP MF CC |
|
SERPINA1 |
10 |
BP MF CC |
biological_process | - acute-phase response
- blood coagulation
- inflammatory response
- negative regulation of endopeptidase activity
more... - platelet activation
- platelet degranulation
- regulation of proteolysis
- response to chromate
- response to cytokine stimulus
- response to estradiol stimulus
- response to hypoxia
- response to lead ion
- response to lipopolysaccharide
- response to methanol
- response to organic cyclic compound
- response to triglyceride
less...
|
| cellular_component | - extracellular region
- extracellular space
- platelet alpha granule lumen
- proteinaceous extracellular matrix
more...
|
| molecular_function | - protease binding
- protein binding
- serine-type endopeptidase inhibitor activity
|
| |
RPS19 |
10 |
BP MF CC |
biological_process | - RNA metabolic process
- anatomical structure development
- cellular protein metabolic process
- endocrine pancreas development
more... - erythrocyte differentiation
- gas transport
- gene expression
- mRNA metabolic process
- positive regulation of cellular component movement
- rRNA processing
- response to extracellular stimulus
- ribosomal small subunit biogenesis
- translation
- translational elongation
- translational termination
- viral infectious cycle
- viral reproduction
- viral transcription
less...
|
| cellular_component | - cytosol
- cytosolic small ribosomal subunit
- intracellular
- nucleolus
more... - nucleus
- ribosome
less...
|
| molecular_function | - RNA binding
- protein binding
- structural constituent of ribosome
|
| |
HSP90AA1 |
10 |
BP MF CC |
biological_process | - ATP catabolic process
- G2/M transition of mitotic cell cycle
- axon guidance
- cellular chaperone-mediated protein complex assembly
more... - mitochondrial transport
- mitotic cell cycle
- nitric oxide metabolic process
- positive regulation of nitric oxide biosynthetic process
- protein folding
- protein import into mitochondrial outer membrane
- protein refolding
- regulation of nitric-oxide synthase activity
- response to stress
- response to unfolded protein
- signal transduction
less...
|
| cellular_component | - cytoplasm
- cytosol
- intracellular
- melanosome
more... - plasma membrane
less...
|
| molecular_function | - ATP binding
- ATPase activity
- TPR domain binding
- identical protein binding
more... - nitric-oxide synthase regulator activity
- nucleotide binding
- protein binding
- protein homodimerization activity
- protein serine/threonine kinase activity
- unfolded protein binding
less...
|
| |
ITGB5 |
10 |
BP MF CC |
biological_process | - cell adhesion
- cell-matrix adhesion
- integrin-mediated signaling pathway
- multicellular organismal development
more... - muscle contraction
less...
|
| cellular_component | - integral to membrane
- integrin complex
- plasma membrane
|
| molecular_function | - protein binding
- receptor activity
|
| |
CCNB1 |
10 |
BP MF CC |
biological_process | - G1/S transition of mitotic cell cycle
- G2/M transition of mitotic cell cycle
- anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
- cell cycle checkpoint
more... - cell division
- cellular response to fatty acid
- cellular response to hypoxia
- cellular response to iron(III) ion
- cellular response to organic cyclic compound
- digestive tract development
- in utero embryonic development
- mitotic cell cycle
- mitotic cell cycle spindle checkpoint
- mitotic metaphase plate congression
- mitotic prometaphase
- mitotic spindle stabilization
- negative regulation of gene expression
- negative regulation of protein phosphorylation
- oocyte maturation
- positive regulation of attachment of spindle microtubules to kinetochore
- positive regulation of cardiac muscle cell proliferation
- positive regulation of histone phosphorylation
- positive regulation of mRNA 3'-end processing
- positive regulation of mitotic cell cycle
- positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
- protein complex assembly
- regulation of chromosome condensation
- regulation of cyclin-dependent protein kinase activity
- regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
- response to DDT
- response to drug
- response to mechanical stimulus
- response to toxin
- spermatogenesis
- tissue regeneration
- ventricular cardiac muscle cell development
less...
|
| | molecular_function | - histone kinase activity
- kinase activity
- protein binding
- protein kinase binding
more...
|
| |
THOC5 |
8 |
BP MF CC |
biological_process | - RNA splicing
- cell differentiation
- intronless viral mRNA export from host nucleus
- mRNA export from nucleus
more... - mRNA processing
- monocyte differentiation
- negative regulation of macrophage differentiation
- primitive hemopoiesis
- transport
less...
|
| | molecular_function | - RNA binding
- protein binding
|
| |
RECK |
8 |
BP MF CC |
biological_process | - negative regulation of endopeptidase activity
|
| cellular_component | - anchored to membrane
- membrane fraction
- peripheral to membrane of membrane fraction
- plasma membrane
more...
|
| molecular_function | - endopeptidase inhibitor activity
- metalloendopeptidase inhibitor activity
- serine-type endopeptidase inhibitor activity
|
| |
CCNO |
8 |
BP MF CC |
| | molecular_function | - protein kinase binding
- uracil DNA N-glycosylase activity
|
| |
SPSB1 |
8 |
BP MF CC |
biological_process | - intracellular signal transduction
|
| | | |
CREBBP |
8 |
BP MF CC |
biological_process | - N-terminal peptidyl-lysine acetylation
- cell proliferation
- cellular lipid metabolic process
- gene expression
more... - histone acetylation
- homeostatic process
- innate immune response
- interspecies interaction between organisms
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
- protein complex assembly
- regulation of S phase
- regulation of transcription, DNA-dependent
- response to hypoxia
- signal transduction
- transcription, DNA-dependent
less...
|
| cellular_component | - cytoplasm
- histone acetyltransferase complex
- nuclear body
- nucleoplasm
more... - nucleus
less...
|
| molecular_function | - MyoD binding
- SMAD binding
- acetyltransferase activity
- histone acetyltransferase activity
more... - metal ion binding
- p53 binding
- peroxisome proliferator activated receptor binding
- protein binding
- sequence-specific DNA binding transcription factor activity
- signal transducer activity
- transcription coactivator activity
- transcription factor binding
- transferase activity
- zinc ion binding
less...
|
| |
ZC3H15 |
8 |
BP MF CC |
biological_process | - cytokine-mediated signaling pathway
|
| cellular_component | - cytoplasm
- nucleolus
- nucleus
- plasma membrane
more...
|
| molecular_function | - metal ion binding
- nucleic acid binding
- zinc ion binding
|
| |
CCDC117 |
8 |
BP MF CC |
|
ATP13A3 |
8 |
BP MF CC |
biological_process | - ATP biosynthetic process
- cation transport
|
| cellular_component | - integral to membrane
- membrane
|
| molecular_function | - ATP binding
- ATPase activity
- ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
- hydrolase activity
more... - hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
- metal ion binding
- nucleotide binding
less...
|
| |
GBP2 |
8 |
BP MF CC |
biological_process | - cytokine-mediated signaling pathway
- immune response
- interferon-gamma-mediated signaling pathway
- type I interferon-mediated signaling pathway
more...
|
| | molecular_function | - GTP binding
- GTPase activity
- nucleotide binding
|
| |
COG3 |
8 |
BP MF CC |
biological_process | - ER to Golgi vesicle-mediated transport
- intra-Golgi vesicle-mediated transport
- intracellular protein transport
- protein glycosylation
more... - protein localization to organelle
- protein stabilization
- protein transport
- retrograde vesicle-mediated transport, Golgi to ER
less...
|
| cellular_component | - Golgi apparatus
- Golgi cisterna membrane
- Golgi transport complex
- cis-Golgi network
more... - membrane
less...
|
| molecular_function | - protein binding
- protein transporter activity
|
| |
LSR |
8 |
BP MF CC |
biological_process | - embryo development
- liver development
- regulation of lipid metabolic process
|
| | | |
PPM1K |
8 |
BP MF CC |
biological_process | - protein dephosphorylation
|
| cellular_component | - mitochondrial matrix
- mitochondrion
- protein serine/threonine phosphatase complex
|
| molecular_function | - hydrolase activity
- metal ion binding
- protein serine/threonine phosphatase activity
|
| |
NRAS |
8 |
BP MF CC |
biological_process | - MAPKKK cascade
- Ras protein signal transduction
- actin cytoskeleton organization
- activation of MAPKK activity
more... - axon guidance
- blood coagulation
- epidermal growth factor receptor signaling pathway
- insulin receptor signaling pathway
- leukocyte migration
- nerve growth factor receptor signaling pathway
- positive regulation of Rac protein signal transduction
- positive regulation of cell proliferation
- regulation of long-term neuronal synaptic plasticity
- regulation of synaptic transmission, GABAergic
- signal transduction
- small GTPase mediated signal transduction
- striated muscle cell differentiation
- visual learning
less...
|
| cellular_component | - Golgi apparatus
- Golgi membrane
- membrane fraction
- plasma membrane
more...
|
| molecular_function | - GTP binding
- GTPase activity
- Ral guanyl-nucleotide exchange factor activity
- nucleotide binding
more...
|
| |
TFAP2C |
8 |
BP MF CC |
biological_process | - cell-cell signaling
- cerebral cortex development
- dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
- epithelial cell proliferation involved in mammary gland duct elongation
more... - forebrain neuron fate commitment
- germ-line stem cell maintenance
- hair follicle development
- keratinocyte development
- male gonad development
- negative regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription from RNA polymerase II promoter
- regulation of epidermis development
- regulation of transcription from RNA polymerase II promoter
- sebaceous gland development
- skin development
- somatic stem cell maintenance
- transcription, DNA-dependent
- trophectodermal cell differentiation
less...
|
| | molecular_function | - DNA binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
- RNA polymerase II distal enhancer sequence-specific DNA binding
more... - protein binding
- protein dimerization activity
- sequence-specific DNA binding RNA polymerase II transcription factor activity
- sequence-specific DNA binding transcription factor activity
less...
|
| |
PNKD |
8 |
BP MF CC |
| cellular_component | - cytoplasm
- membrane
- mitochondrion
- nucleus
more...
|
| molecular_function | - hydrolase activity
- hydroxyacylglutathione hydrolase activity
- metal ion binding
- zinc ion binding
more...
|
| |
FDX1L |
8 |
BP MF CC |
biological_process | - electron transport chain
- transport
|
| cellular_component | - mitochondrial matrix
- mitochondrion
|
| molecular_function | - 2 iron, 2 sulfur cluster binding
- electron carrier activity
- metal ion binding
|
| |
FBP1 |
8 |
BP MF CC |
|
MPV17 |
8 |
BP MF CC |
| cellular_component | - integral to membrane
- integral to peroxisomal membrane
- membrane
- mitochondrial inner membrane
more... - mitochondrion
less...
|
| | |
SLAMF6 |
8 |
BP MF CC |
| cellular_component | - integral to membrane
- plasma membrane
|
| | |
VASH2 |
8 |
BP MF CC |
biological_process | - positive regulation of angiogenesis
- positive regulation of endothelial cell proliferation
|
| | | |
SLC25A33 |
8 |
BP MF CC |
| cellular_component | - integral to membrane
- membrane
- mitochondrial inner membrane
- mitochondrion
more...
|
| | |
NMT1 |
8 |
BP MF CC |
| cellular_component | - actin cytoskeleton
- cell junction
- cytoplasm
- cytosol
more... - plasma membrane
less...
|
| molecular_function | - catalytic activity
- glycylpeptide N-tetradecanoyltransferase activity
- transferase activity
- transferase activity, transferring acyl groups
more...
|
| |
MTCH2 |
8 |
BP MF CC |
| cellular_component | - integral to membrane
- membrane
- mitochondrial inner membrane
- mitochondrion
more...
|
| | |
MYL6B |
8 |
BP MF CC |
biological_process | - muscle contraction
- muscle filament sliding
- skeletal muscle tissue development
|
| cellular_component | - cytosol
- muscle myosin complex
- myosin complex
- unconventional myosin complex
more...
|
| molecular_function | - calcium ion binding
- motor activity
- protein binding
- structural constituent of muscle
more...
|
| |
ANGEL2 |
8 |
BP MF CC |
|
TMEM179B |
8 |
BP MF CC |
| cellular_component | - integral to membrane
- membrane
|
| | |
CALCOCO1 |
8 |
BP MF CC |
biological_process | - Wnt receptor signaling pathway
- positive regulation of transcription, DNA-dependent
- signal transduction
- steroid hormone receptor signaling pathway
more... - transcription, DNA-dependent
less...
|
| | molecular_function | - armadillo repeat domain binding
- beta-catenin binding
- ligand-dependent nuclear receptor transcription coactivator activity
- protein C-terminus binding
more... - protein binding
- sequence-specific DNA binding
- transcription coactivator activity
- transcription cofactor activity
- transcription regulatory region DNA binding
less...
|
| |
MED12 |
8 |
BP MF CC |
biological_process | - androgen receptor signaling pathway
- gene expression
- negative regulation of Wnt receptor signaling pathway
- positive regulation of transcription from RNA polymerase II promoter
more... - positive regulation of transcription, DNA-dependent
- regulation of transcription from RNA polymerase II promoter
- steroid hormone receptor signaling pathway
- transcription initiation from RNA polymerase II promoter
less...
|
| cellular_component | - mediator complex
- nucleoplasm
- nucleus
|
| molecular_function | - RNA polymerase II transcription cofactor activity
- beta-catenin binding
- ligand-dependent nuclear receptor transcription coactivator activity
- protein C-terminus binding
more... - protein domain specific binding
- receptor activity
- thyroid hormone receptor binding
- transcription coactivator activity
- transcription cofactor activity
- vitamin D receptor binding
less...
|
| |
MVP |
8 |
BP MF CC |
biological_process | - mRNA transport
- protein transport
- response to drug
|
| | | |
MOXD1 |
8 |
BP MF CC |
biological_process | - catecholamine metabolic process
- cellular process
- oxidation-reduction process
|
| cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- membrane
more...
|
| molecular_function | - copper ion binding
- dopamine beta-monooxygenase activity
- metal ion binding
- monooxygenase activity
more...
|
| |
PPA1 |
8 |
BP MF CC |
biological_process | - diphosphate metabolic process
- gene expression
- phosphate-containing compound metabolic process
- tRNA aminoacylation for protein translation
more...
|
| | molecular_function | - hydrolase activity
- inorganic diphosphatase activity
- magnesium ion binding
|
| |
SCN11A |
8 |
BP MF CC |
biological_process | - ion transport
- response to drug
- sodium ion transport
- transmembrane transport
more...
|
| cellular_component | - C-fiber
- integral to membrane
- plasma membrane
- voltage-gated sodium channel complex
more...
|
| molecular_function | - voltage-gated ion channel activity
- voltage-gated sodium channel activity
|
| |
REC8 |
8 |
BP MF CC |
biological_process | - M phase of mitotic cell cycle
- male meiosis I
- meiosis
- mitotic cell cycle
more... - mitotic metaphase/anaphase transition
- mitotic prometaphase
- oocyte maturation
- reciprocal meiotic recombination
- sister chromatid cohesion
- spermatid development
- spermatogenesis
- synapsis
less...
|
| cellular_component | - condensed nuclear chromosome, centromeric region
- lateral element
- male germ cell nucleus
- meiotic cohesin complex
more... - nucleoplasm
- nucleus
less...
|
| | |
GLTSCR1 |
8 |
BP MF CC |
|
IFRD1 |
8 |
BP MF CC |
biological_process | - adult somatic muscle development
- multicellular organismal development
- muscle cell differentiation
- myoblast cell fate determination
more...
|
| | | |
AGGF1 |
8 |
BP MF CC |
| cellular_component | - cytoplasm
- extracellular region
- intracellular
- perinuclear region of cytoplasm
more...
|
| molecular_function | - eukaryotic cell surface binding
- nucleic acid binding
- protein binding
|
| |
BDP1 |
8 |
BP MF CC |
biological_process | - regulation of transcription, DNA-dependent
- transcription from RNA polymerase III promoter
|
| | | |
RAPH1 |
8 |
BP MF CC |
biological_process | - cell-matrix adhesion
- signal transduction
|
| cellular_component | - cytoplasm
- cytoskeleton
- filopodium
- lamellipodium
more... - nucleus
- plasma membrane
less...
|
| | |
TRIM6 |
8 |
BP MF CC |
| | molecular_function | - metal ion binding
- molecular_function
- zinc ion binding
|
| |
CLN5 |
8 |
BP MF CC |
|
RDH11 |
8 |
BP MF CC |
biological_process | - retinoid metabolic process
- retinol metabolic process
- steroid metabolic process
|
| cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- intracellular
more... - membrane
less...
|
| molecular_function | - NADP-retinol dehydrogenase activity
- binding
- oxidoreductase activity
- retinol dehydrogenase activity
more...
|
| |
TSR1 |
8 |
BP MF CC |
|
EHMT2 |
8 |
BP MF CC |
biological_process | - DNA methylation
- chromatin modification
- fertilization
- histone H3-K27 methylation
more... - histone H3-K9 methylation
- negative regulation of transcription from RNA polymerase II promoter
- organ growth
- pachytene
- peptidyl-lysine dimethylation
- spermatid development
- synaptonemal complex assembly
less...
|
| | molecular_function | - histone methyltransferase activity (H3-K27 specific)
- histone methyltransferase activity (H3-K9 specific)
- histone-lysine N-methyltransferase activity
- metal ion binding
more... - methyltransferase activity
- p53 binding
- protein binding
- protein-lysine N-methyltransferase activity
- transferase activity
- zinc ion binding
less...
|
| |
CEPT1 |
8 |
BP MF CC |
biological_process | - lipid metabolic process
- phospholipid biosynthetic process
|
| cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- membrane
more... - nuclear membrane
- nucleus
less...
|
| molecular_function | - diacylglycerol cholinephosphotransferase activity
- ethanolaminephosphotransferase activity
- metal ion binding
- phosphotransferase activity, for other substituted phosphate groups
more... - transferase activity
less...
|
| |
VWA3B |
8 |
BP MF CC |
|
TFCP2L1 |
8 |
BP MF CC |
biological_process | - cell morphogenesis
- cytoplasm organization
- determination of adult lifespan
- epithelial cell maturation
more... - female pregnancy
- negative regulation of transcription from RNA polymerase II promoter
- positive regulation of growth
- regulation of transcription from RNA polymerase II promoter
- salivary gland development
- steroid biosynthetic process
- transcription, DNA-dependent
less...
|
| cellular_component | - cytoplasm
- membrane
- mitochondrion
- nucleolus
more... - nucleus
less...
|
| molecular_function | - DNA binding
- sequence-specific DNA binding transcription factor activity
- transcription corepressor activity
|
| |
N4BP1 |
8 |
BP MF CC |
biological_process | - negative regulation of proteasomal ubiquitin-dependent protein catabolic process
- negative regulation of protein ubiquitination
|
| | | |
ZMAT2 |
8 |
BP MF CC |
| | molecular_function | - DNA binding
- metal ion binding
- zinc ion binding
|
| |
SNRPC |
8 |
BP MF CC |
biological_process | - nuclear mRNA splicing, via spliceosome
- spliceosomal snRNP assembly
|
| cellular_component | - Cajal body
- U1 snRNP
- nucleus
- ribonucleoprotein complex
more...
|
| | |
PPAP2A |
8 |
BP MF CC |
biological_process | - activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway
- androgen receptor signaling pathway
- germ cell migration
- lipid metabolic process
more... - negative regulation of cell proliferation
- phospholipid dephosphorylation
- regulation of lipid metabolic process
- sphingolipid metabolic process
- steroid hormone receptor signaling pathway
less...
|
| cellular_component | - integral to plasma membrane
- membrane fraction
- plasma membrane
|
| molecular_function | - hydrolase activity
- phosphatidate phosphatase activity
|
| |
WAC |
8 |
BP MF CC |
biological_process | - cell cycle checkpoint
- chromatin modification
- histone H2B conserved C-terminal lysine ubiquitination
- histone monoubiquitination
more... - positive regulation of transcription, DNA-dependent
- response to DNA damage stimulus
less...
|
| cellular_component | - nuclear speck
- nucleus
- spliceosomal complex
|
| molecular_function | - RNA polymerase II core binding
- chromatin binding
- protein binding
|
| |
DHRS11 |
8 |
BP MF CC |
| | molecular_function | - binding
- oxidoreductase activity
|
| |
MAF |
8 |
BP MF CC |
biological_process | - transcription from RNA polymerase II promoter
|
| | molecular_function | - sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
|
| |
RELA |
8 |
BP MF CC |
biological_process | - MyD88-dependent toll-like receptor signaling pathway
- MyD88-independent toll-like receptor signaling pathway
- T cell receptor signaling pathway
- Toll signaling pathway
more... - acetaldehyde metabolic process
- aging
- anti-apoptosis
- cellular defense response
- cellular response to lipopolysaccharide
- cytokine-mediated signaling pathway
- defense response
- defense response to virus
- hair follicle development
- inflammatory response
- innate immune response
- interspecies interaction between organisms
- liver development
- membrane protein intracellular domain proteolysis
- negative regulation of apoptosis
- negative regulation of insulin receptor signaling pathway
- negative regulation of protein catabolic process
- negative regulation of transcription, DNA-dependent
- nerve growth factor receptor signaling pathway
- nucleotide-binding oligomerization domain containing 2 signaling pathway
- organ morphogenesis
- positive regulation of I-kappaB kinase/NF-kappaB cascade
- positive regulation of NF-kappaB transcription factor activity
- positive regulation of Schwann cell differentiation
- positive regulation of cell proliferation
- positive regulation of chondrocyte differentiation
- positive regulation of interleukin-12 biosynthetic process
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription, DNA-dependent
- regulation of inflammatory response
- response to UV-B
- response to amino acid stimulus
- response to bacterium
- response to cAMP
- response to cobalamin
- response to cytokine stimulus
- response to drug
- response to hydrogen peroxide
- response to inorganic substance
- response to insulin stimulus
- response to interleukin-1
- response to mechanical stimulus
- response to morphine
- response to muramyl dipeptide
- response to organic cyclic compound
- response to organic substance
- response to progesterone stimulus
- toll-like receptor 1 signaling pathway
- toll-like receptor 2 signaling pathway
- toll-like receptor 3 signaling pathway
- toll-like receptor 4 signaling pathway
- toll-like receptor signaling pathway
- transcription, DNA-dependent
less...
|
| | molecular_function | - DNA binding
- NF-kappaB binding
- activating transcription factor binding
- ankyrin repeat binding
more... - chromatin binding
- identical protein binding
- phosphate ion binding
- protein N-terminus binding
- protein binding
- protein kinase binding
- repressing transcription factor binding
- sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
- sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
- transcription factor binding
- transcription regulatory region DNA binding
- ubiquitin protein ligase binding
less...
|
| |
GPD1L |
8 |
BP MF CC |
biological_process | - carbohydrate metabolic process
- glycerol-3-phosphate catabolic process
- oxidation-reduction process
|
| cellular_component | - cytoplasm
- glycerol-3-phosphate dehydrogenase complex
|
| molecular_function | - NAD binding
- binding
- glycerol-3-phosphate dehydrogenase [NAD+] activity
- protein homodimerization activity
more...
|
| |
CNN3 |
8 |
BP MF CC |
biological_process | - actomyosin structure organization
- smooth muscle contraction
|
| | molecular_function | - actin binding
- calmodulin binding
- tropomyosin binding
- troponin C binding
more...
|
| |
NDUFA9 |
8 |
BP MF CC |
| | molecular_function | - 3-beta-hydroxy-delta5-steroid dehydrogenase activity
- NADH dehydrogenase (ubiquinone) activity
- NADH dehydrogenase activity
- binding
more... - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
less...
|
| |
SLCO2A1 |
8 |
BP MF CC |
biological_process | - lipid transport
- sodium-independent organic anion transport
- transmembrane transport
|
| cellular_component | - integral to plasma membrane
- membrane
- membrane fraction
- plasma membrane
more...
|
| molecular_function | - lipid transporter activity
- prostaglandin transmembrane transporter activity
- transporter activity
|
| |
IDH3A |
8 |
BP MF CC |
biological_process | - 2-oxoglutarate metabolic process
- NADH metabolic process
- carbohydrate metabolic process
- isocitrate metabolic process
more... - tricarboxylic acid cycle
less...
|
| cellular_component | - mitochondrial matrix
- mitochondrion
|
| molecular_function | - NAD binding
- isocitrate dehydrogenase (NAD+) activity
- magnesium ion binding
- oxidoreductase activity
more... - oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
less...
|
| |
TMEM147 |
8 |
BP MF CC |
| cellular_component | - endoplasmic reticulum
- endoplasmic reticulum membrane
- integral to membrane
- membrane
more...
|
| | |
DNAJB14 |
8 |
BP MF CC |
| cellular_component | - integral to membrane
- membrane
|
| molecular_function | - heat shock protein binding
- unfolded protein binding
|
| |
MAGI3 |
8 |
BP MF CC |
biological_process | - apoptosis
- interspecies interaction between organisms
- intracellular signal transduction
|
| | molecular_function | - ATP binding
- guanylate kinase activity
- nucleotide binding
- protein binding
more...
|
| |
GJC1 |
8 |
BP MF CC |
biological_process | - cardiac muscle tissue development
- cell development
- cell-cell junction assembly
- cellular membrane organization
more... - gap junction assembly
- muscle contraction
- synaptic transmission
- transport
- vasculogenesis
- visual perception
less...
|
| | | |
XPO1 |
8 |
BP MF CC |
biological_process | - M phase of mitotic cell cycle
- RNA metabolic process
- interspecies interaction between organisms
- intracellular protein transport
more... - mRNA metabolic process
- mRNA transport
- mitotic cell cycle
- mitotic prometaphase
- negative regulation of transcription from RNA polymerase II promoter
- protein localization to nucleus
- regulation of centrosome duplication
- regulation of protein catabolic process
- regulation of protein export from nucleus
- response to drug
- viral genome transport in host cell
- viral infectious cycle
- viral reproduction
less...
|
| | | |
ACAT2 |
8 |
BP MF CC |
| cellular_component | - cytoplasm
- mitochondrion
- nucleolus
- nucleus
more...
|
| molecular_function | - acetyl-CoA C-acetyltransferase activity
- transferase activity
- transferase activity, transferring acyl groups other than amino-acyl groups
|
| |
KATNB1 |
8 |
BP MF CC |
biological_process | - cell cycle
- cell division
- microtubule severing
- mitosis
more... - negative regulation of microtubule depolymerization
- positive regulation of cell death
- positive regulation of microtubule depolymerization
- positive regulation of neuron projection development
- protein targeting
less...
|
| | molecular_function | - dynein binding
- microtubule binding
- microtubule-severing ATPase activity
- protein heterodimerization activity
more...
|
| |
FAM149A |
8 |
BP MF CC |
|
HMGA2 |
8 |
BP MF CC |
biological_process | - DNA damage response, detection of DNA damage
- base-excision repair
- cell cycle
- cell division
more... - chondrocyte differentiation
- chondrocyte proliferation
- chromatin organization
- chromosome breakage
- chromosome condensation
- endodermal cell differentiation
- epithelial to mesenchymal transition
- fat cell differentiation
- heterochromatin formation
- histone H2A-S139 phosphorylation
- mesenchymal cell differentiation
- mesodermal cell differentiation
- mesodermal-endodermal cell signaling
- mitosis
- mitotic cell cycle G2/M transition DNA damage checkpoint
- multicellular organismal development
- negative regulation by host of viral transcription
- negative regulation of DNA binding
- negative regulation of apoptosis
- negative regulation of double-strand break repair via nonhomologous end joining
- negative regulation of retroviral genome replication
- negative regulation of transcription from RNA polymerase II promoter
- negative regulation of transcription, DNA-dependent
- oncogene-induced senescence
- positive regulation of apoptosis
- positive regulation of cell cycle arrest
- positive regulation of cellular response to X-ray
- positive regulation of cellular senescence
- positive regulation of gene expression
- positive regulation of response to DNA damage stimulus
- positive regulation of stem cell proliferation
- positive regulation of transcription from RNA polymerase II promoter
- positive regulation of transcription regulatory region DNA binding
- positive regulation of transcription, DNA-dependent
- regulation of cell cycle process
- regulation of cellular response to drug
- regulation of growth
- regulation of stem cell maintenance
- regulation of transcription, DNA-dependent
- response to virus
- senescence-associated heterochromatin focus formation
- stem cell differentiation
less...
|
| | molecular_function | - 5'-deoxyribose-5-phosphate lyase activity
- AT DNA binding
- C2H2 zinc finger domain binding
- DNA bending activity
more... - DNA binding
- DNA-(apurinic or apyrimidinic site) lyase activity
- DNA-dependent protein kinase activity
- MH1 domain binding
- MH2 domain binding
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
- SMAD binding
- cAMP response element binding
- core promoter binding
- nucleic acid binding transcription factor activity
- nucleosomal DNA binding
- protein binding
- protein binding transcription factor activity
- regulatory region DNA binding
- transcription factor binding
less...
|
| |
TGIF2 |
8 |
BP MF CC |
biological_process | - positive regulation of neuron differentiation
- regulation of transcription, DNA-dependent
- retina development in camera-type eye
- transcription, DNA-dependent
more...
|
| | molecular_function | - sequence-specific DNA binding
- sequence-specific DNA binding transcription factor activity
|
| |
ATP5B |
8 |
BP MF CC |
biological_process | - ADP biosynthetic process
- ATP biosynthetic process
- ATP catabolic process
- ATP hydrolysis coupled proton transport
more... - ATP metabolic process
- ATP synthesis coupled proton transport
- angiogenesis
- generation of precursor metabolites and energy
- ion transport
- lipid metabolic process
- mitochondrial ATP synthesis coupled proton transport
- negative regulation of cell adhesion involved in substrate-bound cell migration
- proton transport
- receptor-mediated endocytosis
- regulation of intracellular pH
- respiratory electron transport chain
- transport
less...
|
| cellular_component | - cell surface
- mitochondrial matrix
- mitochondrial membrane
- mitochondrial nucleoid
more... - mitochondrial proton-transporting ATP synthase complex
- mitochondrial proton-transporting ATP synthase, catalytic core
- mitochondrion
- plasma membrane
- proton-transporting ATP synthase complex, catalytic core F(1)
- proton-transporting two-sector ATPase complex
less...
|
| molecular_function | - ATP binding
- ATPase activity
- MHC class I protein binding
- calcium ion binding
more... - eukaryotic cell surface binding
- hydrogen ion transporting ATP synthase activity, rotational mechanism
- hydrogen-exporting ATPase activity, phosphorylative mechanism
- hydrolase activity
- hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
- lipoprotein particle receptor activity
- nucleoside-triphosphatase activity
- nucleotide binding
- protein binding
- proton-transporting ATPase activity, rotational mechanism
- transmembrane transporter activity
- transporter activity
less...
|
| |
ZCCHC11 |
8 |
BP MF CC |
biological_process | - RNA 3'-end processing
- cytokine production
- gene silencing by RNA
- histone mRNA catabolic process
more... - miRNA catabolic process
- miRNA metabolic process
- negative regulation of NF-kappaB transcription factor activity
- pre-miRNA processing
- regulation of lipopolysaccharide-mediated signaling pathway
- stem cell maintenance
less...
|
| cellular_component | - cytoplasm
- nucleolus
- nucleus
|
| | |
IFT88 |
8 |
BP MF CC |
biological_process | - anterior/posterior pattern specification
- brain development
- cardiac septum morphogenesis
- cell projection organization
more... - cilium morphogenesis
- determination of left/right symmetry
- dorsal/ventral pattern formation
- embryonic digit morphogenesis
- embryonic organ development
- forebrain morphogenesis
- in utero embryonic development
- lung vasculature development
- nervous system development
- organ morphogenesis
- positive regulation of proteolysis
- protein processing
- regulation of odontogenesis of dentine-containing tooth
- smoothened signaling pathway
- telencephalon development
less...
|
| cellular_component | - axoneme
- centriole
- cilium
- cytoplasm
more... - cytoskeleton
- intraflagellar transport particle B
- microtubule basal body
- microtubule-based flagellum
- motile primary cilium
less...
|
| | |
RMND5B |
8 |
BP MF CC |
|